Results 121 to 130 of about 2,085 (265)

Model Choice Matters for Age Inference on the Red Giant Branch

The Astrophysical Journal
Galactic archaeology relies on accurate stellar parameters to reconstruct the Galaxy's history, including information on stellar ages. While the precision of data has improved significantly in recent years, stellar models used for age inference have not ...
Leslie M. Morales, Jamie Tayar, Zachary R. Claytor   +2 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

A Galactic Interloper: A Study of the Camelopardis OB1 Association’s Clusters and Its Visitor from the Perseus Arm

The Astrophysical Journal
Within the molecular clouds of the Camelopardis OB1 (Cam OB1) association exists a region previously noted as one subgroup. However, bulk clustering from Gaia astrometry has recently shown three distinctive kinematically coherent groups, all found in a ...
Joseph Mullen, Amanda Mast, Marina Kounkel, Keivan Stassun, Alexandre Roman-Lopes, Jonathan C. Tan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

[C/N] Ages and Extra Mixing for [Fe/H] < −0.5: Insights from the LMC and SMC

The Astrophysical Journal
The [C/N]–age relation has become a powerful tool for reconstructing the formation history of the Milky Way (MW), providing the largest age sample for field giant stars.
Yuxi(Lucy) Lu, John D. Roberts, Joshua T. Povick, Marc H. Pinsonneault, Madeline Howell, David L. Nidever, Jennifer A. Johnson   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Stellar Age Inference with Rotation (+ Activity?)

Ages of low mass main sequence (MS) stars can be challenging to measure because of their long MS lifetimes. While gyrochronology (a method of dating such stars using rotation period) is somewhat effective, the observed dispersion in rotation rates for similar coeval stars has historically been difficult to model.
Van-Lane, Phil, Speagle, Joshua Shen, Eadie, Gwendolyn, Douglas, Stephanie T., Cloutier, Ryan, Cargile, Phillip, Zucker, Catherine, Lu, Yuxi, Angus, Ruth   +8 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

The Milky Way bulge stellar ages

, 2019
A number of recent photometric and spectroscopic surveys are producing a comprehensive and coherent picture of the Milky Way bulge through the detailed properties of its stellar content. While there is a general consensus on the overall morphology, 3D structure, kinematics and metallicity of the bulge, a still debated question regards the age of its ...
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source