Results 91 to 100 of about 1,216,320 (294)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Planetary-nebula Central Stars as Tracers of Planetary-nebula–Star-cluster Associations in the Galaxy

The Astrophysical Journal
Planetary nebulae (PNs) that are physically associated with star clusters are rare but crucial for stellar-evolution studies because they allow their initial and final stellar properties to be determined independently, contributing to constraints on the ...
Vasiliki Fragkou, Luis Lomelí-Núñez, Dante Minniti, Arianna Cortesi, Denise R. Gonçalves   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

GULP. II. Hierarchical Distribution and Evolution of Young Stellar Structures in NGC 4449

The Astrophysical Journal
We investigate the hierarchical distribution and evolution of young stellar structures in the dwarf starburst galaxy NGC 4449 using data from the GULP survey.
Beena Meena, Elena Sabbi, Peter Zeidler, Bruce G. Elmegreen, Jan J. Eldridge, Varun Bajaj, Mario Gennaro, Anna Pasquali, Debra M. Elmegreen, Ralf S. Klessen, Linda J. Smith, Luciana Bianchi, Aida Wofford, Pietro Facchini, John S. Gallagher III, Daniela Calzetti, Eva K. Grebel, Angela Adamo, (GULP)   +18 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A Census of Chemically Peculiar Stars in Stellar Associations

Astronomy
The pre-main-sequence evolution of the chemically peculiar (CP) stars on the upper main sequence is still a vast mystery and not well understood. Our analysis of young associations and open clusters aims to find (very) young CP stars to try to put a ...
Lukas Kueß, Ernst Paunzen
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The Timescales of Embedded Star Formation as Observed in STARFORGE

The Astrophysical Journal
Star formation occurs within dusty molecular clouds that are then disrupted by stellar feedback. However, the timing and physical mechanisms that govern the transition from deeply embedded to exposed stars remain uncertain.
Tobin M. Wainer, Julianne J. Dalcanton, Michael Y. Grudić, Stella S. R. Offner, Adam Smercina, Benjamin F. Williams, L. Clifton Johnson, J. Peltonen, Eric W. Koch, Kartik R. Neralwar   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

On the Group Formation of Stars in Stellar Associations [PDF]

International Astronomical Union Colloquium, 1982
The discovery and study of stellar associations by Ambartsumian (1947, 1954 a) proved two fundamental points regarding the star formation process, e.g., Mirzoyan, 1976. One of them is that the formation process still continues in the present evolution of the Galaxy, and this thesis is not disputed now.
openaire   +1 more source