Results 101 to 110 of about 1,216,320 (294)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

SPYGLASS. VI. Feedback-driven Star Formation in the Circinus Complex

The Astrophysical Journal
Young associations provide a record that traces the star formation process, and the youngest populations connect progenitor gas dynamics to the resulting stellar populations.
Ronan Kerr, Juan P. Farias, Lisa Prato, Travis A. Rector, Joshua S. Speagle, Adam L. Kraus   +5 more
doaj   +1 more source

Wolf–Rayet stars as tracers of gamma-ray emission

Astronomy & Astrophysics
Context. Recent gamma-ray observations of young star clusters revealed that stellar wind termination shocks accelerate particles. The energy reservoir for particle acceleration is provided by the wind mechanical power of cluster member stars. Aims.
Inventar A., Peron G., Recchia S., Gabici S.   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The evolution of velocity dispersion in the Sco-Cen OB association

Astronomy & Astrophysics
We study how the stellar velocity dispersion within the Scorpius-Centaurus OB association (Sco-Cen) has evolved over approximately 20 million years, from its formation to the present day, by investigating 32 stellar clusters in Sco-Cen.
Großschedl Josefa E., Alves João, Ratzenböck Sebastian, Miret-Roig Núria, Hutschenreuter Sebastian, Posch Laura, Hacar Alvaro   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A deep HST view of the open cluster NGC2158: Binaries, mass functions, and M-dwarf discontinuity

Astronomy & Astrophysics
A significant fraction of stars in both the Galactic field and stellar clusters belong to binary systems. Understanding their properties is therefore fundamental for a comprehensive picture of stellar structure, stellar evolution, and cluster dynamics ...
Marchuk A. V., Muratore F., Milone A. P., Legnardi M. V., D’Antona F., Cordoni G., Mastrobuono-Battisti A., Bortolan E., Dell’Agli F., Dondoglio E., Lagioia E. P., Marino A. F., Tailo M., Ventura C., Ventura P., Ziliotto T.   +15 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Radio-loud Semiregular Variable

The Astrophysical Journal
As a byproduct of our search for Galactic stellar systems with gamma-ray emission, we have identified an unrelated cool and evolved star (IRC-10412) that attracted our attention due to its strong radio emission level with a spectral index matching ...
Pedro L. Luque-Escamilla, Josep Martí
doaj   +1 more source