Results 111 to 120 of about 92,482 (301)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Pressure in Stellar Atmospheres [PDF]

Nature, 1911
WITHIN the last fifteen years the spectroscopic equipment applied to the study of both laboratory and celestial investigation has been very materially modified both in dispersive power and design. In the early nineties there were very few of the 21.5-feet Rowland concave grating spectrographs in regular commission for terrestrial research, and it is ...
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Constraints on Quaoar’s Rings and Atmosphere from JWST/NIRCam Observations of a Stellar Occultation

The Planetary Science Journal
Observations of stellar occultations have revealed that small bodies are capable of hosting ring systems. The trans-Neptunian object Quaoar is the host of an enigmatic ring system, with two rings located well outside the Roche limit. To better understand
Benjamin Proudfoot, Bryan J. Holler, Ko Arimatsu, Flavia L. Rommel, Cameron Collyer, Estela Fernández-Valenzuela   +5 more
doaj   +1 more source

Balloon atmospheric propagation experiment measurements [PDF]

High altitude balloon measurements on laser beam fading during propagation through turbulent atmosphere show that a correlation between fading strength and stellar scintillation magnitudes exists.
Minott, P. O.
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Stellar Chromospheric Activity

Living Reviews in Solar Physics, 2008
The Sun, stars similar to it, and many rather dissimilar to it, have chromospheres, regions classically viewed as lying above the brilliant photosphere and characterized by a positive temperature gradient and a marked departure from radiative equilibrium.
Hall Jeffrey C.
doaj  

On the variation of the microturbulence parameter with chemical composition [PDF]

Stellar model atmosphere abundance analysis to correlate microturbulent velocity parameters with iron to hydrogen ratio for G ...
Strom, S. E.
core   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

The Physician‐Scientist Pipeline for Pediatric Rheumatology – Current Landscape and Future Perspectives.

Arthritis Care &Research, Accepted Article.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu, Linda T. Hiraki, Mara L. Becker   +2 more
wiley   +1 more source