Results 91 to 100 of about 92,482 (301)

A Deep Chandra X-ray Spectrum of the Accreting Young Star TW Hydrae

open access: yes, 2010
We present X-ray spectral analysis of the accreting young star TW Hydrae from a 489 ks observation using the Chandra High Energy Transmission Grating.
A. K. Dupree   +43 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

An HST Transmission Spectrum of the Closest M Dwarf Transiting Rocky Planet LTT 1445Ab

open access: yesThe Astronomical Journal
Which rocky exoplanets have atmospheres? This presumably simple question is the first that must be answered to understand the prevalence of nearby habitable planets.
Katherine A. Bennett   +9 more
doaj   +1 more source

Role of local absorption on the X-ray emission from MHD accretion shocks in classical T Tauri stars

open access: yesEPJ Web of Conferences, 2014
Accretion processes onto classical T Tauri stars (CTTSs) are believed to generate shocks at the stellar surface due to the impact of supersonic downflowing plasma.
Bonito   +8 more
doaj   +1 more source

Analysis of stellar spectra with 3D and NLTE models

open access: yes, 2014
Models of radiation transport in stellar atmospheres are the hinge of modern astrophysics. Our knowledge of stars, stellar populations, and galaxies is only as good as the theoretical models, which are used for the interpretation of their observed ...
A Chiavassa   +64 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Stellar Models Also Limit Exoplanet Atmosphere Studies in Emission

open access: yesThe Astrophysical Journal
Stellar contamination has long been recognized as a major bottleneck in transmission spectroscopy, limiting our ability to accurately characterize exoplanet atmospheres—particularly for terrestrial worlds.
Thomas J. Fauchez   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Promise and Peril: Stellar Contamination and Strict Limits on the Atmosphere Composition of TRAPPIST-1 c from JWST NIRISS Transmission Spectra

open access: yesThe Astrophysical Journal Letters
Attempts to probe the atmospheres of rocky planets around M dwarfs present both promise and peril. While their favorable planet-to-star radius ratios enable searches for even thin secondary atmospheres, their high activity levels and high-energy outputs ...
Michael Radica   +11 more
doaj   +1 more source

The Collisional Atomic Processes of Rydberg Hydrogen and Helium Atoms: Astrophysical Relevance

open access: yesGalaxies, 2018
Elementary processes in astrophysical environments traditionally attract researchers’ attention. We present the data needed for the inclusion of the specific atomic collisional processes in the investigation of the optical and kinetic properties of
Vladimir A. Srećković   +4 more
doaj   +1 more source

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