Results 81 to 90 of about 92,482 (301)

Model atmospheres of chemically peculiar stars: Self-consistent empirical stratified model of HD24712

open access: yes, 2009
High-resolution spectra of some chemically peculiar stars clearly demonstrate the presence of strong abundance gradients in their atmospheres. However, these inhomogeneities are usually ignored in the standard scheme of model atmosphere calculations ...
Alecian   +54 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The relationship between photometric and spectroscopic oscillation amplitudes from 3D stellar atmosphere simulations. [PDF]

open access: yesMon Not R Astron Soc, 2021
Zhou Y   +7 more
europepmc   +1 more source

The CARMENES search for exoplanets around M dwarfs - Photospheric parameters of target stars from high-resolution spectroscopy

open access: yes, 2018
The new CARMENES instrument comprises two high-resolution and high-stability spectrographs that are used to search for habitable planets around M dwarfs in the visible and near-infrared regime via the Doppler technique.
Amado, P. J.   +16 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Exploring the Small-scale Magnetic Fields of the Solar Analog KIC 8006161 Using Asteroseismology

open access: yesThe Astrophysical Journal
The magnetic field is a significant and universal physical phenomenon in modern astrophysics. Small-scale magnetic fields are very important in the stellar atmosphere. They are ubiquitous and strongly couple with acoustic waves. Therefore, their presence
Guifang Lin   +4 more
doaj   +1 more source

The chemical composition of normal stellar atmospheres [PDF]

open access: yes
Spectroscopic analysis of stellar atmosphere chemical ...
Aller, L. H.
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Additional JWST/NIRSpec Transits of the Rocky M Dwarf Exoplanet GJ 1132 b Reveal a Featureless Spectrum

open access: yesThe Astronomical Journal
As an archetypal M-dwarf rocky exoplanet, GJ 1132 b has a varied history of atmospheric measurements. At 1.13 R _⊕ , 1.66 M _⊕ , and 580 K, it orbits a bright, slowly rotating M dwarf in a 1.6 day period, making it a prime target for characterization. In
Katherine A. Bennett   +19 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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