Results 121 to 130 of about 820,585 (334)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

INFLUENCE OF SHOCK WAVES ON THE LIGHT CURVES OF LONG-PERIOD VARIABLES

Odessa Astronomical Publications, 2017
The shapes of light curves of Mira-type variable stars is analyzed. It is shown that some features of the light curves may be explained by passage of shock waves in the stars' atmospheres. In particular, it is noted that "steps" of the ascending branches
L. S. Kudashkina, G. M. Rudnitskij
doaj   +1 more source

Performance Triggered Adaptive Model Reduction for Soil Moisture Estimation in Precision Irrigation

International Journal of Adaptive Control and Signal Processing, EarlyView.
ABSTRACT Accurate soil moisture information is essential for precise irrigation to enhance water use efficiency. Estimating soil moisture based on limited soil moisture sensors is especially critical for obtaining comprehensive soil moisture information when dealing with large‐scale agricultural fields.
Sarupa Debnath, Bernard Twum Agyeman, Soumya Ranjan Sahoo, Xunyuan Yin, Jinfeng Liu   +4 more
wiley   +1 more source

The Future of Observational Stellar Atmospheres [PDF]

Highlights of Astronomy, 1974
The title of this talk is, of course, a bit absurd since no one in his right mind can possibly predict what will happen in the future over even one year let alone ten. However nothing is impossible for Dick Thomas and having accepted his invitation to present this talk I have to pretend to have a crystal ball and put up a good front.
openaire   +2 more sources

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Dissociation Energy of Carbon Monoxide and the Abundance of Elements in Stellar Atmospheres [PDF]

, 1936
M.−A. Nicolet
openalex   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Stellar Contamination Correction Using Back-to-back Transits of TRAPPIST-1 b and c

The Astrophysical Journal Letters
Stellar surface heterogeneities, such as spots and faculae, often contaminate exoplanet transit spectra, hindering precise atmospheric characterization.
Alexander D. Rathcke, Lars A. Buchhave, Julien de Wit, Benjamin V. Rackham, Prune C. August, Hannah Diamond-Lowe, João M. MendonÇa, Aaron Bello-Arufe, Mercedes López-Morales, Daniel Kitzmann, Kevin Heng   +10 more
doaj   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source