Results 101 to 110 of about 6,001 (306)

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Physics of Eclipsing Binaries. VI. Hot, Compact Stars

The Astrophysical Journal Supplement Series
Models of eclipsing binaries require the assignment of appropriate emergent intensities to the surface elements of the binary components. For distance-dependent modeling of flux-calibrated light curves, this necessitates an approximation of the absolute ...
David Jones, Nicole Reindl, Kyle E. Conroy, James Munday, Pier-Emmanuel Tremblay, Michael Abdul-Masih, Matthias Fabry, Joseph Giammarco, Kelly M. Hambleton, Herbert Pablo, Marcin Wrona, Andrej Prša   +11 more
doaj   +1 more source

Status and future of hydrodynamical model atmospheres [PDF]

, 2005
Since about 25 years ago work has been dedicated to the development of hydrodynamical model atmospheres for cool stars (of A to T spectral type). Despite their obviously sounder physical foundation in comparison with standard hydrostatic models, their ...
Ludwig, Hans-Günter, Kucinskas, Arunas
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Impact of stellar spots on the high-resolution transmission spectra of a giant planet around a Sun-like star

Astronomy & Astrophysics
Context. Transmission spectroscopy has enabled the analysis of exoplanet atmospheres. However, a major challenge in this field is the “noise” from host stars, caused by stellar activity such as dark spots and bright plages.
Lucero Jennifer P., Demangeon O. D. S., Cristo E., Dethier W., Santos N. C.   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The Influence of Stellar Chromospheres and Coronae on Exoplanet Transmission Spectroscopy

The Astrophysical Journal Letters
A main source of bias in transmission spectroscopy of exoplanet atmospheres is magnetic activity of the host star in the form of stellar spots, faculae, or flares. However, the fact that main-sequence stars have a chromosphere and a corona and that these
Volker Perdelwitz, Adam Chaikin-Lifshitz, Aviv Ofir, Oded Aharonson   +3 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Empirical Prediction of Plasma Emission Measure Distributions and X-Ray/Extreme-ultraviolet Spectra of Late-type Stars

The Astrophysical Journal
High-energy emission spectra from the outer atmospheres of late-type stars represent an important feature of the stellar activity in several contexts, such as the photoevaporation and photochemistry of planetary atmospheres or the modeling of irradiated ...
A. Maggio, I. Pillitteri, J. Sanz-Forcada, G. Micela   +3 more
doaj   +1 more source