Results 111 to 120 of about 215,434 (305)
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
The Astrophysical JournalHigh-energy emission spectra from the outer atmospheres of late-type stars represent an important feature of the stellar activity in several contexts, such as the photoevaporation and photochemistry of planetary atmospheres or the modeling of irradiated ...
A. Maggio +3 more
doaj +1 more source
Carbon abundances in the light of 3D model stellar atmospheres
, 2016 Classical spectroscopic analyses of late-type stars generally rely on the interpretation of observations with the use of stationary, one-dimensional (1D), hydrostatic model stellar atmospheres.
Collet, Remo (5266984), Collet, Remo
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Microlensing and the Physics of Stellar Atmospheres
, 2000 8 pages including 6 figures. To appear in ``Microlensing 2000: A New Era of Microlensing Astrophysics,'' an ASP conference proceedings, eds. J.W.
openaire +3 more sources
Status and future of hydrodynamical model atmospheres
, 2005 Since about 25 years ago work has been dedicated to the development of hydrodynamical model atmospheres for cool stars (of A to T spectral type). Despite their obviously sounder physical foundation in comparison with standard hydrostatic models, their ...
Ludwig, Hans-Günter, Kucinskas, Arunas
core
Hydrodynamic simulations of cool stellar atmospheres with
Context. Three-dimensional time-dependent simulations of stellar atmospheres are essential to study the surface of stars other than the Sun. These simulations require the opacity binning method to reduce the computational cost of solving the radiative ...
N. Vitas +3 more
core +1 more source