Results 91 to 100 of about 2,528,028 (339)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The IACOB project XII. A new grid of northern standards for the spectral classification of B-type stars [PDF]

A&A 690, A176 (2024)
With the advent of large spectroscopic surveys, automated stellar parameter determination has become commonplace. Nevertheless, spectral classification still offers a quick and useful alternative for obtaining parameter estimates for large samples of spectra of varying quality.
arxiv   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

A Spectroscopic Survey of Metal-poor OB Stars in Local Dwarf Galaxy NGC 3109

The Astrophysical Journal
As JWST uncovers increasingly strong evidence that metal-poor, massive stars in early galaxies dominated reionization, observational constraints on the properties of such stars are more relevant than ever before.
Abby Mintz, O. Grace Telford, Evan N. Kirby, John Chisholm, Kristen B. W. McQuinn, Danielle A. Berg   +5 more
doaj   +1 more source

Automated Classification of ELODIE Stellar Spectral Library Using Probabilistic Artificial Neural Networks [PDF]

Bull.Astron.Soc.India 36:1-54,2008, 2008
A Probabilistic Neural Network model has been used for automated classification of ELODIE stellar spectral library consisting of about 2000 spectra into 158 known spectro-luminosity classes. The full spectra with 561 flux bins and a PCA reduced set of 57, 26 and 16 components have been used for the training and test sessions.
arxiv  

Probing the dusty stellar populations of the Local Volume Galaxies with JWST/MIRI [PDF]

, 2017
The Mid-Infrared Instrument (MIRI) for the {\em James Webb Space Telescope} (JWST) will revolutionize our understanding of infrared stellar populations in the Local Volume. Using the rich {\em Spitzer}-IRS spectroscopic data-set and spectral classifications from the Surveying the Agents of Galaxy Evolution (SAGE)-Spectroscopic survey of over a thousand
arxiv   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Classification of Astronomical Spectra Based on Multiscale Partial Convolution

The Astronomical Journal
The automated and efficient classification of astronomical spectra is an important research issue in the era of large sky surveys. Most current studies on automatic spectral classification primarily focus on specific data sets and demonstrate outstanding
Jingjing Wu, Yuchen He, Wenyu Wang, Meixia Qu, Bin Jiang, Yanxia Zhang   +5 more
doaj   +1 more source