Results 111 to 120 of about 1,941,056 (293)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Cooperative AI Techniques for Stellar Spectra Classification

, 2006
This chapter describes a hybrid approach to the unattended classification of low-resolution optical spectra of stars. The classification of stars in the standard MK system constitutes an important problem in the astrophysics area, since it helps to carry
Alejandra Rodriguez, Carlos Dafonte, Iciar Carricajo, Minia Manteiga, Bernardino Arcay   +4 more
core   +1 more source

FALCO: Foundation Model of Astronomical Light Curves for Time Domain Astronomy. Implementation and Applications on Kepler Data

The Astronomical Journal
Time-domain surveys have advanced astronomical research by revealing diverse variable phenomena, from stellar flares to transient events. The scale and complexity of survey data, along with the demand for rapid classification, present significant ...
Xiaoxiong Zuo, Yihan Tao, Yang Huang, Zhixuan Kang, Huaxi Chen, Chenzhou Cui, Jiashu Pan, Xiao Kong, Yuan-Sen Ting, Xiaoyu Tang, Henggeng Han, Haiyang Mu, Yunfei Xu, Dongwei Fan, Guirong Xue, Ali Luo, Jifeng Liu   +16 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Cooperative AI Techniques for Stellar Spectra Classification

, 2008
This chapter describes a hybrid approach to the unattended classification of low-resolution optical spectra of stars. The classification of stars in the standard MK system constitutes an important problem in the astrophysics area, since it helps to carry
Alejandra Rodriguez, Carlos Dafonte, Iciar Carricajo, Minia Manteiga, Bernardino Arcay   +4 more
core   +1 more source

Classification of Wolf–Rayet Stars from LAMOST DR10

The Astrophysical Journal Supplement Series
Wolf–Rayet (WR) stars are highly evolved descendants of the most massive initial stellar populations, serving as essential tracers in stellar evolution. Despite the progress made in their study, a more comprehensive population census is still required to
Jirui Chang, Wenyu Wang, Meixia Qu, Kun Su, Liangping Tu, Chenyang Lv, Bin Jiang, Yanxia Zhang   +7 more
doaj   +1 more source

Diffraction-driven photometry: A novel method for stellar temperature determination

Astronomy & Astrophysics
Context. Estimating stellar temperatures is a fundamental task in astrophysics, typically achieved using colour indices (CI) derived from multi-filter photometry.
Bonaque-González Sergio, Ríos-Rodríguez Susana, de Varona Omar, Martín-Rodríguez Leopoldo L., Molina Pablo   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

USmorph: An Updated Framework of Automatic Classification of Galaxy Morphologies and Its Application to Galaxies in the COSMOS Field

The Astrophysical Journal Supplement Series
Morphological classification conveys abundant information on the formation, evolution, and environment of galaxies. In this work, we refine a two-step galaxy morphological classification framework ( USmorph ), which employs a combination of unsupervised ...
Jie Song, GuanWen Fang, Shuo Ba, Zesen Lin, Yizhou Gu, Chichun Zhou, Tao Wang, Cai-Na Hao, Guilin Liu, Hongxin Zhang, Yao Yao, Xu Kong   +11 more
doaj   +1 more source