Results 71 to 80 of about 64,602 (241)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Advances in Spectral Classification [PDF]

, 2010
In this article we give an overview of the developments in the field of spectral classification and its continued importance in the fields of stellar and galactic evolution.
Giridhar, Sunetra
core  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

ELUCID IV: Galaxy Quenching and its Relation to Halo Mass, Environment, and Assembly Bias

, 2017
We examine the quenched fraction of central and satellite galaxies as a function of galaxy stellar mass, halo mass, and the matter density of their large scale environment.
Bosch, Frank C. van den, Chen, Sihan, Cui, Weiguang, Huang, Shuiyao, Jing, Yipeng, Kang, Xi, Li, Guoliang, Li, Shijie, Lim, S. H., Lin, Weipeng, Lu, Yi, Mo, H. J., Shi, Feng, Tweed, Dylan, Wang, Enci, Wang, Huiyuan, Wei, Chengliang, Yang, Xiaohu, Yang, Yang, Zhang, Youcai   +19 more
core   +1 more source

Automated classification of stellar spectra [PDF]

, 2020
Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2020, Tutor: Josep Maria Solanes MajúaWe have analyzed the performance of a PCA-based automated classifier of stellar spectra into the MK system, using as benchmark ...
Jiménez Palau, Cristina
core  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Notes on Stellar Classification [PDF]

, 1915
Norman Lockyer
openalex   +3 more sources

Classification of Astronomical Spectra Based on Multiscale Partial Convolution

The Astronomical Journal
The automated and efficient classification of astronomical spectra is an important research issue in the era of large sky surveys. Most current studies on automatic spectral classification primarily focus on specific data sets and demonstrate outstanding
Jingjing Wu, Yuchen He, Wenyu Wang, Meixia Qu, Bin Jiang, Yanxia Zhang   +5 more
doaj   +1 more source

Classification of variable stars in the WFCAM Transit Survey

EPJ Web of Conferences, 2013
The WFCAM Transit Survey is a photometric survey in the near-infrared and aims at finding Earth-like planets transiting M-dwarf stars. As a by-product of the survey, a variety of variable stars has been detected.
Moya Andrés, Barrado David, Sarro Luis M., Stoev Hristo   +3 more
doaj   +1 more source