Results 61 to 70 of about 4,703 (262)

Hedgehog: An Isolated Quiescent Dwarf Galaxy at 2.4 Mpc

open access: yesThe Astrophysical Journal Letters
It is well known that almost all isolated dwarf galaxies are actively forming stars. We report the discovery of dw1322m2053 (nicknamed Hedgehog), an isolated quiescent dwarf galaxy at a distance of 2.40 ± 0.15 Mpc with a stellar mass of M _⋆ ≈ 10 ^5.8 M ...
Jiaxuan Li   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Mapping the Distant and Metal-poor Milky Way with SDSS-V

open access: yesThe Astrophysical Journal
The fifth-generation Sloan Digital Sky Survey (SDSS-V) is conducting the first all-sky low-resolution spectroscopic survey of the Milky Way’s (MW) stellar halo.
Vedant Chandra   +30 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Ages, Distances, and the Initial Mass Functions of Stellar Clusters [PDF]

open access: yes, 2000
13 pages, including 3 embedded figures (4 EPS files). To appear in "11th Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun," ed. R. J. Garcia Lopez, R. Rebolo, and M. R.
Stauffer, JR   +3 more
openaire   +2 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The Interplay of Stellar Evolution and Collisions in Galactic Nuclei

open access: yesThe Astrophysical Journal
Nuclear star clusters (NSCs) surrounding supermassive black holes (SMBHs) are among the densest stellar environments in the Universe. In these environments, collisions can shape the stellar mass function and produce exotic stellar populations.
Jaden S. Sidhu   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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