Results 81 to 90 of about 4,703 (262)
A Deep, High-angular-resolution 3D Dust Map of the Southern Galactic Plane
The Astrophysical JournalWe present a deep, high-angular-resolution 3D dust map of the southern Galactic plane over 239°
Catherine Zucker +10 more
doaj +1 more source
Astronomy & AstrophysicsUnderstanding supernova (SN) progenitors remains a major challenge in astrophysics, as it involves untangling the complex interplay between stellar physics (e.g. evolution, binarity, and explosion) and environments (e.g.
Gutiérrez Claudia P. +6 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The Astrophysical JournalIn NGC 2992, a galaxy-scale ionized gas outflow driven by active galactic nuclei (AGNs) has long been recognized, yet its impact on the host galaxy has remained elusive.
Xiaoyu Xu +3 more
doaj +1 more source
Gaia, Stellar Populations and the Distance Scale
, 2018 We discuss the impact that Gaia, a European Space Agency (ESA) cornerstone mission that has been in scientific operations since July 2014, is expected to have on the definition of the cosmic distance ladder and the study of resolved stellar populations in and beyond the Milky Way, specifically focusing on results based on Cepheids and RR Lyrae stars ...
Clementini, Gisella +3 more
openaire +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Wolf–Rayet stars as tracers of gamma-ray emission
Astronomy & AstrophysicsContext. Recent gamma-ray observations of young star clusters revealed that stellar wind termination shocks accelerate particles. The energy reservoir for particle acceleration is provided by the wind mechanical power of cluster member stars. Aims.
Inventar A. +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source