Results 101 to 110 of about 4,703 (262)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Mapping the Milky Way in 5D with 170 Million Stars

The Astrophysical Journal
We present Augustus , a catalog of distance, extinction, and stellar parameter estimates for 170 million stars from 14 mag < r < 20 mag and with ∣ b ∣ > 10° drawing on a combination of optical to near-infrared photometry from Pan-STARRS, 2MASS, UKIDSS ...
Joshua S. Speagle, Catherine Zucker, Ana Bonaca, Phillip A. Cargile, Benjamin D. Johnson, Angus Beane, Charlie Conroy, Douglas P. Finkbeiner, Gregory M. Green, Harshil M. Kamdar, Rohan Naidu, Hans-Walter Rix, Edward F. Schlafly, Aaron Dotter, Gwendolyn Eadie, Daniel J. Eisenstein, Alyssa A. Goodman, Jiwon Jesse Han, Andrew K. Saydjari, Yuan-Sen Ting, Ioana A. Zelko   +20 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Detecting Stellar Coronal Mass Ejections via Coronal Dimming in the Extreme Ultraviolet

The Astrophysical Journal
Stellar flares and coronal mass ejections (CMEs) can strip planetary atmospheres, reducing the potential habitability of terrestrial planets. While flares have been observed for decades, stellar CMEs remain elusive.
James Paul Mason, Allison Youngblood, Kevin France, Astrid M. Veronig, Meng Jin   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

An AI-ready Stellar Dataset Assembled from LAMOST DR11

The Astrophysical Journal Supplement Series
We present a clean, homogeneous, and AI-ready stellar dataset assembled from LAMOST DR11 low-resolution spectra, tailored for data-driven models. This dataset contains 111,417 high-quality spectra for 91,542 AFGK-type stars, with stellar labels such as T
Bing Du, A-Li Luo, Yi-Han Song, Ke-Fei Wu, Yun-Xiao Jia, Ying-Long Cui, Yi-Han Tao, Fang Zuo, Wen Hou, Yan-Xin Guo, Xiao Kong   +10 more
doaj   +1 more source

The extinction distances for over a thousand planetary nebulae with Gaia measurements

Astronomy & Astrophysics
Context. Although Gaia has identified the central stars of planetary nebulae (CSPNe) for about 70% of known Galactic planetary nebulae (PNe), reliable distance estimates remain highly incomplete, with fewer than one quarter having accurate parallaxes ...
Deng Juan, Wang Shu, Jiang Biwei, Deng Licai   +3 more
doaj   +1 more source

The Determination of Stellar Distances [PDF]

Nature, 1922
openaire   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Catalog of Distance Determinations for 5 Million Stars in LAMOST DR10

The Astronomical Journal
Using the distance estimation method outlined in J. L. Carlin et al., a Bayesian approach specifically tailored for LAMOST data, we estimated distances for 7,450,303 spectra from 5,394,174 unique stars in the LAMOST DR10 low-resolution data set.
Chengqun Yang, Xiang-Xiang Xue, Chao Liu, Hao Tian, Ling Zhu, Lan Zhang   +5 more
doaj   +1 more source