Results 101 to 110 of about 12,062 (300)
Stellar population variations in the Milky Way's stellar halo [PDF]
, 2010 If the stellar halos of disk galaxies are built up from the disruption of dwarf galaxies, models predict highly structured variations in the stellar populations within these halos.Christine Ruhland, Bell, Eric F., Xiang Xiang Xue, Ruhland, Christine, Hogg, David W., Eric F. Bell, Rix, Hans-Walter, Xue, Xiang Xiang, Hans-Walter Rix, David W. Hogg +9 morecore +1 more sourceCell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis +10 morewiley +1 more sourceThe First Systematic Survey of Stellar Halos in High-inclination Galaxies Reveals Unusually Quiescent Merger Histories of Nearby Galaxies
The Astrophysical Journal Supplement SeriesStellar halos are the only major stellar component of disk galaxies that lack systematic observational characterization, yet they encode critical information about galaxy merger histories.Bojun Tao, Hong-Xin Zhang, Wenting Wang, Enci Wang, Guangwen Chen, Huiyuan Wang, Lijun Chen, Qian-Hui Chen, Song Huang, Xu Kong, Yu Rong +10 moredoaj +1 more sourceMultiplicity of Galactic Cepheids from long-baseline interferometry I. CHARA/MIRC detection of the companion of V1334 Cygni
, 2013 W.G. and G.P. acknowledge financial support for this work from the BASAL Centro de Astrofísica y Tecnologías Afines (CATA) PFB-06/2007. Support from the Polish National Science Centre grant MAESTRO and the Polish Ministry of Science grant Ideas Plus ...Monnier, J., Mérand, Antoine, Pietrzyński, Grzegorz, F. Baron, Gallenne, Alexandre, ten Brummelaar, T., G. H. Schaefer, C. Farrington, Monnier, J. D., G. Pietrzyński, Gieren, W., E. Pedretti, Pietrzynski, G., Schaefer, G.~H., N. Vargas, Che, X., Kervella, P., Kraus, S., McAlister, H., Turner, N., J. D. Monnier, L. Szabados, Pedretti, E., N. Turner, A. Mérand, Kervella, Pierre, P. Kervella, Pietrzyski, G., S. Kraus, A. Gallenne, Schaefer, G., Baron, F., Monnier, J.~D., L. Sturmann, Szabados, László, X. Che, Schaefer, G. H., Szabados, L., Farrington, C., Vargas, N., H. McAlister, T. ten Brummelaar, Merand, A., Sturmann, J., J. Sturmann, Gallenne, A., Sturmann, L., W. Gieren +47 morecore +1 more sourceDistance determination for RAVE stars using stellar models [PDF]
, 2011 We apply the method of Burnett and Binney (2010) for the determination of stellar distances and parameters to the internal catalogue of the Radial Velocity Experiment (Steinmetz et al. 2006).Bienayme, O, O. Bienaymé, M. Williams, Bienaymé, Olivier, Parker, Quentin A., U. Munari, Helmi, A, S. Sharma, J. Fulbright, Binney, James J., Zwitter, T., Grebel, Eva K., Gibson, B., Grebel, E. K., Wyse, R. F. G., Navarro, Julio F., Steinmetz, M., Williams, Mary E K, Sharma, Sanjib, G. M. Seabroke, Grebel, EK, Gibson, B, T. Zwitter, Seabroke, George M., Gibson, Brad K., Steinmetz, Matthias, Munari, Ulisse, F. G. Watson, Munari, U., A. Siviero, Siviero, A., Gilmore, G, Watson, Fred G., Siebert, Arnaud, Williams, M., Fulbright, J., Parker, QA, Freeman, Kenneth C., Steinmetz, M, Burnett, Benedict C M, A. Helmi, Binney, J., Navarro, J. F., Siebert, A., Wyse, RFG, E. K. Grebel, K. C. Freeman, Sharma, S, B. Burnett, Siviero, Alessandro, Watson, F. G., Munari, U, A. Siebert, Sharma, S., Seabroke, G. M., Bland-Hawthorn, J., Bland-Hawthorn, J, Parker, Q. A., Bienaymé, O., Bland-Hawthorn, Joss Bland, M. Steinmetz, Freeman, KC, Watson, FG, G. Gilmore, Helmi, A., R. F. G. Wyse, Freeman, K. C., Burnett, B, Zwitter, T, J. Bland-Hawthorn, B. Gibson, Seabroke, GM, Zwitter, Tomaž, Helmi, Amina, Q. A. Parker, Gilmore, G., Binney, J, Fulbright, J, J. F. Navarro, Burnett, B., Williams, M, Siebert, A, Gilmore, Gerard F., Fulbright, Jon P., J. Binney, Siviero, A, Navarro, JF +86 morecore +1 more sourceHijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...Gabriela Marinescu, Yi Fengwiley +1 more sourceESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou +12 morewiley +1 more sourcephotoD with Rubin’s Data Preview 1: First stellar photometric distances and faint blue star deficits
Astronomy & AstrophysicsAims. We investigate the utility of Rubin’s Data Preview 1 (DP1) for estimating stellar number density profiles across the Milky Way halo.
Methods.Palaversa L., Donev E., Ivezić Ž., Mrakovčić K., Caplar N., Jurićc M., Jurkić T., Campos S., DeLucchi M., Jones D., Malanchev K., Malz A. I., McGuire S., Abel B., Girardi L., Pastorelli G., Trabucchi M., Zaggia S., Acosta E., Adair C. L., Andrew J., Aubourg É., Bauer A. E., Beebe W., Bellm E. C., Blum R. D., Booth M. T., Boucaud A., Branton D., Burke D. L., Calabrese D., Carlin J. L., Chiang H.-F., Choi Y., Connolly A. J., Dagoret-Campagne S., Daly P. N., Daruich F., Daubard G., Dennihy E., Drass H., Eiger O., Eisner A. M., Guy L. P., Hoblitt J., Ingraham P., Jammes F., Jannuzi B. T., Jee M. J., Jenness T., Jones R. L., Juramy-Gilles C., Kahn S. M., Kang Y., Kannawadi A., Kelvin L. S., Kotov I. V., Kovács G., Kurita N. R., Lange T., Laporte D., Lazarte J. C., Liang S., Lopez M., Lust N. B., Lutfi M., Lynn O., Mainetti G., Menanteau F., Miller M., Moniez M., Nourbakhsh E., Park H. Y., Peterson J. R., Plante R., Plazas Malagón A. A., Porter M. N., Reil K. A., Riot V. J., Roodman A., Rykoff E. S., Schindler R. H., Sebag J., Sedaghat N., Shaw R. A., Shugart A., Siruno K. B., Smith J. A., Swinbank J. D., Thayer J. G., Thomas S., Tighe R., Tucker D. L., Turri M., Urbach E. K., Van Klaveren B., van Reeven W., Waters C. Z., Willman B. +98 moredoaj +1 more sourceEROS differential studies of Cepheids in the Magellanic Clouds : Stellar pulsation, stellar evolution and distance scale [PDF]
, 1996 : We present a differential study of 500 Magellanic Cepheids with 3 million measurements obtained as a by-product of the EROS microlensing survey. The data-set is unbiased and provides an excellent basis for a differential analysis between LMC and SMC ...Sasselov, D. D.,, Beaulieu, J. P., Sasselov, D. D., Beaulieu, J. P., +3 morecore Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo +7 morewiley +1 more source
