Results 91 to 100 of about 1,747,943 (295)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Ages, Distances, and the Initial Mass Functions of Stellar Clusters [PDF]
, 2000 13 pages, including 3 embedded figures (4 EPS files). To appear in "11th Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun," ed. R. J. Garcia Lopez, R. Rebolo, and M. R.
Stauffer, JR +3 more
openaire +2 more sources
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
The Interplay of Stellar Evolution and Collisions in Galactic Nuclei
The Astrophysical JournalNuclear star clusters (NSCs) surrounding supermassive black holes (SMBHs) are among the densest stellar environments in the Universe. In these environments, collisions can shape the stellar mass function and produce exotic stellar populations.
Jaden S. Sidhu +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 1996 This workshop item forms the first of a series of three presented jointly by the University of the West Indies and the International Extension College.
The Distance Education Center of the University of the West Indies and The International Extension College Training Link
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Astrophysical Journal Supplement SeriesStellar halos are the only major stellar component of disk galaxies that lack systematic observational characterization, yet they encode critical information about galaxy merger histories.
Bojun Tao +10 more
doaj +1 more source
Gaia, Stellar Populations and the Distance Scale
, 2018 We discuss the impact that Gaia, a European Space Agency (ESA) cornerstone mission that has been in scientific operations since July 2014, is expected to have on the definition of the cosmic distance ladder and the study of resolved stellar populations in and beyond the Milky Way, specifically focusing on results based on Cepheids and RR Lyrae stars ...
Clementini, Gisella +3 more
openaire +2 more sources