Results 71 to 80 of about 1,747,943 (295)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Determining Stellar Elemental Abundances from DESI Spectra with the Data-driven Payne
The Astrophysical Journal Supplement SeriesStellar abundances for a large number of stars provide key information for the study of Galactic formation history. Large spectroscopic surveys such as the Dark Energy Spectroscopic Instrument (DESI) and LAMOST take median-to-low-resolution ( R ≲ 5000 ...
Meng Zhang +10 more
doaj +1 more source
EPJ Web of Conferences, 2015 Clusters are excellent test benches for verification and improvement of stellar evolution theory. The recent detection of solar-like oscillations in G-K giants in the open cluster NGC6819 with Kepler provides us with independent constraints on the masses
Lagarde, N +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
THE STEADY-STATE WIND MODEL FOR YOUNG STELLAR CLUSTERS WITH AN EXPONENTIAL STELLAR DENSITY DISTRIBUTION [PDF]
, 2011 A hydrodynamic model for steady-state, spherically symmetric winds driven by young stellar clusters with an exponential stellar density distribution is presented.
GUILLERMO TENORIO TAGLE +2 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Astrophysical JournalOver the past few decades, an increasing number of transients in nearby galaxies have been discovered through various survey projects. Unlike astrophysical phenomena at cosmological distances, transients in the local Universe exhibit a pronounced ...
Ye-Hao Cheng, Yuan-Pei Yang, Ye Li
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Type II Cepheids: period-luminosity-metallicity relations for the Population II distance scale
Frontiers in Astronomy and Space SciencesType II Cepheids are a class of pulsating variable stars that play a critical role in our understanding of stellar evolution, distance measurement and tracing the structure and kinematics of old stars in nearby galaxies.
Susmita Das +4 more
doaj +1 more source