Results 71 to 80 of about 4,703 (262)

The First Systematic Survey of Stellar Halos in High-inclination Galaxies Reveals Unusually Quiescent Merger Histories of Nearby Galaxies

open access: yesThe Astrophysical Journal Supplement Series
Stellar halos are the only major stellar component of disk galaxies that lack systematic observational characterization, yet they encode critical information about galaxy merger histories.
Bojun Tao   +10 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Imaging Magnetically Driven Astrospheres: A Forward Modeling Approach

open access: yesThe Astrophysical Journal Letters
An astrosphere is a vast, tailed, bubble-like volume around a star, formed through the interaction between the stellar magnetic field, the stellar wind, and the interstellar medium (ISM).
Ziqi Wu   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

photoD with Rubin’s Data Preview 1: First stellar photometric distances and faint blue star deficits

open access: yesAstronomy & Astrophysics
Aims. We investigate the utility of Rubin’s Data Preview 1 (DP1) for estimating stellar number density profiles across the Milky Way halo. Methods.
Palaversa L.   +98 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Important considerations of Stellar distance indicators

open access: yes, 2020
Periodic luminous pulses are very important for measurements in Cosmology and Astrophysics, and there are very specific methods and sources which exhibit such properties. Stellar astrophysics provides a number of observational and mathematical sources which give a very important tool in understanding the dynamics of an expanding Universe, and in this ...
openaire   +2 more sources

The Impact of Stellar Distances on Habitable Zone Planets [PDF]

open access: yesThe Astrophysical Journal Letters, 2018
Abstract Among the most highly valued of exoplanetary discoveries are those of terrestrial planets found to reside within the habitable zone (HZ) of the host star. In particular, those HZ planets with relatively bright host stars will serve as priority targets for characterization observations, such as those involving mass determinations,
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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