Results 141 to 150 of about 3,529,940 (309)
Stellar evolution and feedback connections to stellar dynamics [PDF]
AbstractUntil a few years ago, the common paradigm for the formation of Globular Clusters (GCs) was that they constitute a ‘simple stellar population’ in which all the stars were formed from a chemically homogeneous cluster medium within a relatively short interval of time, at the beginning of the galactic life.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Editorial: Galactic Dynamics in the Solar Neighborhood
Jacques R. D. Lépine
doaj +1 more source
Stellar Distributions around Supermassive Black Holes in Gas-rich Nuclear Star Clusters
We study the stellar distribution around supermassive black holes in gas-rich nuclear star clusters (NSCs). NSCs could contain vast amounts of gas, which contribute significantly to shaping the stellar distribution, typically altering the stellar density
Mor Rozner, Enrico Ramirez-Ruiz
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Iron Snails: Nonequilibrium Dynamics and Spiral Abundance Patterns
Galaxies are not in a dynamical steady state: they continually undergo perturbations, e.g., from infalling dwarf galaxies and dark matter substructure. After a dynamical perturbation, stars phase mix toward a new steady state; in so doing, they generally
Neige Frankel +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Predicting images for the dynamics of stellar clusters (π-DOC): a deep learning framework to predict mass, distance, and age of globular clusters [PDF]
Jonathan Chardin, Paolo Bianchini
openalex +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

