Results 41 to 50 of about 4,688 (310)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Internal rotation of red giants by asteroseismology

EPJ Web of Conferences, 2013
We present an asteroseismic approach to study the dynamics of the stellar interior in red giant stars by asteroseismic inversion of the splittings induced by the stellar rotation on the oscillation frequencies.
Christensen-Dalsgaard J., Mosser B., Hekker S., García R.A., Elsworth Y., Davies G., Beck P.G., Stello D., Ventura R., Di Mauro M.P., Cardini D., Bloemen S., Catanzaro G., De Smedt K., Tkachenko A.   +14 more
doaj   +1 more source

Stellar Collisions in the Galactic Center: Massive Stars, Collision Remnants, and Missing Red Giants

The Astrophysical Journal, 2023
Like most galaxies, the Milky Way harbors a supermassive black hole (SMBH) at its center, surrounded by a nuclear star cluster. In this dense star cluster, direct collisions can occur between stars before they evolve off the main sequence.
Sanaea C. Rose, Smadar Naoz, Re’em Sari, Itai Linial   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Dynamics of plance stellar systems [PDF]

Astrophysics and Space Science, 1971
AbstractThe evolution of initially balanced rotating disks of stars is investigated with a computer model for isolated disks of stars. An isolated, initially cold balanced disk is found to be violently unstable. Adding a sufficient amount of velocity dispersion will stabilize all small-scale disturbances.
openaire   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Kinematics of the Young Stellar Population in the W5 Region of the Cassiopeia OB6 Association: Implication for the Formation Process of Stellar Associations

The Astronomical Journal, 2023
The star-forming region W5 is a major part of the Cassiopeia OB6 association. Its internal structure and kinematics may provide hints of the star formation process in this region.
Beomdu Lim, Jongsuk Hong, Jinhee Lee, Hyeong-Sik Yun, Narae Hwang, Byeong-Gon Park   +5 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source