Results 51 to 60 of about 3,956 (262)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Axially Symmetric Post-Newtonian Stellar Systems

Revista Integración, 2010
We introduce a method to obtain self-consistent, axially symmetric disklike stellar models in the first post-Newtonian (1PN) approximation. By using in the field equations of the 1PN approximation a distribution function (DF) corresponding to a ...
Camilo Akímushkin, Javier Ramos-Caro, Guillermo A. González   +2 more
doaj  

Internal rotation of red giants by asteroseismology

EPJ Web of Conferences, 2013
We present an asteroseismic approach to study the dynamics of the stellar interior in red giant stars by asteroseismic inversion of the splittings induced by the stellar rotation on the oscillation frequencies.
Christensen-Dalsgaard J., Mosser B., Hekker S., García R.A., Elsworth Y., Davies G., Beck P.G., Stello D., Ventura R., Di Mauro M.P., Cardini D., Bloemen S., Catanzaro G., De Smedt K., Tkachenko A.   +14 more
doaj   +1 more source

Stellar Collisions in the Galactic Center: Massive Stars, Collision Remnants, and Missing Red Giants

The Astrophysical Journal, 2023
Like most galaxies, the Milky Way harbors a supermassive black hole (SMBH) at its center, surrounded by a nuclear star cluster. In this dense star cluster, direct collisions can occur between stars before they evolve off the main sequence.
Sanaea C. Rose, Smadar Naoz, Re’em Sari, Itai Linial   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Functional Integrals in Stellar Dynamics [PDF]

Symposium - International Astronomical Union, 1985
In the late 70s, the functional integral formulation equivalent to the Fokker-Planck equation was worked out (Graham). We apply this functional integral formulation to gravitationally interacting systems, whose dynamics may be analyzed by separating the forces operating on a particle into a mean field force and fluctuations due to random collisions at ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Stellar dynamics and black holes [PDF]

Pramana, 2011
Chandrasekhar's most important contribution to stellar dynamics was the concept of dynamical friction. I briefly review that work, then discuss some implications of Chandrasekhar's theory of gravitational encounters for motion in galactic nuclei.
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source