Results 41 to 50 of about 3,956 (262)
Stellar Dynamics of Dense Stellar Systems [PDF]
, 2001 10 pages, LaTeX, to appear in the proceedings for the International Symposium on Supercomputing, held in Tokyo, Japan, September 1-3 ...
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Supercomputing and stellar dynamics
, 2009 In this paper I will outline some of the aspects and problems of modern celestial mechanics and stellar dynamics, in the context of the quickly growing computing facilities. I will point the attention on the great advantages in using, for astrophysical simulations, the modern, fast and cheap Graphic Processing Units (GPUs) acting as true supercomputers.
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Astrophysical Journal, 2023 Stars can be either disrupted as tidal disruption events (TDEs) or swallowed whole by massive black holes (MBHs) at galactic centers when they approach sufficiently close to these MBHs.
Yunfeng Chen, Qingjuan Yu, Youjun Lu
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Stellar dynamics of Cen A [PDF]
Monthly Notices of the Royal Astronomical Society, 1986 On a obtenu la premiere carte complete du champ des vitesses stellaires pour les 100 sec. d'arc. autour du noyau de la galaxie elliptique brillante NGC 5128 (Cen A) et on a obtenu des spectres complementaires a longue fente jusqu'a 400 sec. d'arc. suivant l'axe principal optique.
A. Wilkinson +3 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Astronomy & AstrophysicsContext. Earth-like exoplanets can create resonant structures in exozodiacal dust through mean motion resonances. These structures not only suggest the presence of such planets but also act as potential noise sources in future mid-infrared nulling ...
Lee Seung-Yoo +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source