Results 61 to 70 of about 3,320,308 (251)
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Computer Models for Stellar Dynamics Circa 2008
In this brief review I sum up some recent progress in the area of stellar dynamics, focusing on the dynamics of self-bound stellar associations in isolation and in (approximate) equilibrium.
C. M. Boily
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
This study presents a detailed chemical, kinematic, and orbital dynamic analysis of five metal-poor stars in the solar neighborhood: HD 2665, HD 5916, HD 122956, HD 189349, and HD 218857.
Gizay Yolalan +3 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Stellar Streams Reveal the Mass Loss of Globular Clusters
Globular cluster (GC) streams, debris of stars tidally stripped from their progenitor GCs, have densities that correlate positively with the GC mass-loss rate.
Yingtian Chen, Hui Li, Oleg Y. Gnedin
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
StarStream on Gaia: Stream Discovery and Mass-loss Rate of Globular Clusters
We apply the automatic stellar stream detection algorithm StarStream to Gaia Data Release 3 and identify 87 stellar streams associated with Galactic globular clusters (GCs), including 34 high-quality cases with median completeness and purity both ...
Yingtian Chen +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

