Results 81 to 90 of about 4,688 (310)
Sculpting Andromeda – made-to-measure models for M31’s bar and composite bulge: dynamics, stellar and dark matter mass [PDF]
, 2018 M. Blaña +8 more
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Iron Snails: Nonequilibrium Dynamics and Spiral Abundance Patterns
The Astrophysical JournalGalaxies are not in a dynamical steady state: they continually undergo perturbations, e.g., from infalling dwarf galaxies and dark matter substructure. After a dynamical perturbation, stars phase mix toward a new steady state; in so doing, they generally
Neige Frankel +4 more
doaj +1 more source
Stellar evolution and feedback connections to stellar dynamics [PDF]
Proceedings of the International Astronomical Union, 2006 AbstractUntil a few years ago, the common paradigm for the formation of Globular Clusters (GCs) was that they constitute a ‘simple stellar population’ in which all the stars were formed from a chemically homogeneous cluster medium within a relatively short interval of time, at the beginning of the galactic life.
openaire +2 more sources
3D self-consistent N-body barred models of the Milky Way: I. Stellar dynamics [PDF]
, 1997 R. Fux
openalex +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Editorial: Galactic Dynamics in the Solar Neighborhood
Frontiers in Astronomy and Space Sciences, 2022 Jacques R. D. Lépine
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
3-D Dynamics of Interactions between Stellar Winds and the Interstellar Medium as Seen by AKARI and Spitzer [PDF]
, 2009 Toshiya Ueta +11 more
openalex +1 more source