Results 211 to 220 of about 220,693 (280)

Magnetic star-planet interaction in the young exoplanet system DS Tucanae Ab

Santos Ld, Owen J, Duvvuri G, Loyd ROP, Vidotto A, Presa A, Bourrier V, King G, Airapetian V, Ehrenreich D, France K, Lendl M, Lothringer J, Nielsen L.   +13 more
europepmc   +1 more source

Exo-Geoscience Perspectives Beyond Habitability. [PDF]

Space Sci Rev
Spohn T, Roberge A, Way MJ, Duarte JC, Miozzi F, Baumeister P, Byrne P, Lineweaver CH.   +7 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A complex structure of escaping helium spanning more than half the orbit of the ultra-hot Jupiter WASP-121 b. [PDF]

Nat Commun
Allart R, Coulombe LP, Carteret Y, Splinter J, Dang L, Bourrier V, Lafrenière D, Albert L, Artigau É, Benneke B, Cowan NB, Doyon R, Krishnamurthy V, Jayawardhana R, Johnstone D, Langeveld AB, Meyer MR, Pelletier S, Piaulet-Ghorayeb C, Radica M, Taylor J, Turner JD.   +21 more
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Earth-mass planets with He atmospheres in the habitable zone of Sun-like stars. [PDF]

Nat Astron
Lammer H, Scherf M, Erkaev NV, Kubyshkina D, Gorbunova KD, Fossati L, Woitke P.   +6 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Coronal dimmings and what they tell us about solar and stellar coronal mass ejections. [PDF]

Living Rev Sol Phys
Veronig AM, Dissauer K, Kliem B, Downs C, Hudson HS, Jin M, Osten R, Podladchikova T, Prasad A, Qiu J, Thompson B, Tian H, Vourlidas A.   +12 more
europepmc   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Origin of compact exoplanetary systems during disk infall. [PDF]

Nat Commun
Rufu R, Canup RM.
europepmc   +1 more source