Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
The origin of ultra diffuse galaxies: stellar feedback and quenching. [PDF]
Chan TK +7 more
europepmc +1 more source
Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Discrete effects in stellar feedback: Individual Supernovae, Hypernovae, and IMF Sampling in Dwarf Galaxies. [PDF]
Su KY +9 more
europepmc +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
FeedBack 0-1 Contents: Preface, Alicia Miller 3 Introduction to FeedBack, Nayia Yiakoumaki 4 -- Audience – Piracy – Posse: Art Gallery Multitude, Janna Graham 5 -- Tactful Curation, Gair Boase 10 -- El Real Viaje Real, Lillian Davies 13 -- Art ...
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Tracing the Origins of Hot Halo Gas in Milky Way–type Galaxies with SMUGGLE
Current galaxy formation models predict the existence of X-ray-emitting gaseous halos around Milky Way (MW)–type galaxies. To investigate properties of this coronal gas in MW-like galaxies, we analyze a suite of high-resolution simulations based on the ...
Zhijie Zhang +10 more
doaj +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source
The Impact of Stellar Feedback from Massive Stars in the Interstellar Medium [PDF]
The impact of stellar feedback from massive stars is important for the evolution of the interstellar medium and the structures within. Stellar winds, ionizing radiation, and supernovae are considered as the most important processes in shaping molecular ...
Haid, Sebastian
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Stellar Population and Energy Feedback in the Supergiant Shell LMC 1
Supergiant shells (SGSs) are the largest interstellar structures in galaxies and inject hot enriched gas into galactic halos. We have studied SGS LMC 1 to determine quantitatively whether stellar energy feedback is adequate to power the formation of an ...
Guan-Hong Li +6 more
doaj +1 more source

