Results 51 to 60 of about 1,238,105 (253)

Low- and High-velocity O vi in Milky Way-like Galaxies: The Role of Stellar Feedback

open access: yesThe Astrophysical Journal
Milky Way-type galaxies are surrounded by a warm-hot gaseous halo containing a considerable amount of baryons and metals. The kinematics and spatial distribution of highly ionized ion species such as O vi can be significantly affected by supernova (SN ...
Zhijie Zhang   +9 more
doaj   +1 more source

The Kinematic Bimodality: Efficient Feedback and Cold Gas Deficiency in Slow-rotating Galaxies

open access: yesThe Astrophysical Journal Letters, 2023
The bimodality in the stellar spin of low-redshift (massive) galaxies, ubiquitously existing at all star formation levels and in diverse environments, suggests that galaxies grow and quench through two diverged evolutionary pathways.
Bitao Wang, Yingjie Peng
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Exploring the Evolution of a Dwarf Spheroidal Galaxy with Smoothed-particle Hydrodynamics Simulations. I. Stellar Feedback

open access: yesThe Astrophysical Journal
A fundamental question regarding the evolution of dwarf spheroidal galaxies is the identification of the key physical mechanisms responsible for gas depletion.
Roberto Hazenfratz   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Implications of the Nanohertz Gravitational-wave Background for Galactic Feedback and Massive Black Hole Growth

open access: yesThe Astrophysical Journal Letters
We investigate how pulsar timing array (PTA) measurements of the nanohertz gravitational-wave background (GWB) can constrain models for the growth history of supermassive black holes (SMBHs) and how active galactic nucleus (AGN) and stellar feedback ...
Megan Taylor Tillman   +7 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

The role of stellar feedback on the structure of the ISM and star formation in galaxies. [PDF]

open access: yes, 2017
Stellar feedback refers to the injection of energy, momentum and mass into the interstellar medium (ISM) by massive stars. This feedback owes to a combination of ionising radiation, radiation pressure, stellar winds and supernovae and is likely ...
Grisdale, Kearn
core   +1 more source

The AGORA High-resolution Galaxy Simulations Comparison Project. VIII. Disk Formation and Evolution of Simulated Milky Way Mass Galaxy Progenitors at 1 < z < 5

open access: yesThe Astrophysical Journal
We investigate how differences in the stellar feedback produce disks with different morphologies in Milky Way–like progenitors over 1 ≤ z ≤ 5, using eight state-of-the-art cosmological hydrodynamics simulation codes in the AGORA project.
Minyong Jung   +27 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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