Results 61 to 70 of about 3,312 (299)
The Astrophysical JournalDue to their inability to self-regulate, ultrafaint dwarfs are sensitive to prescriptions in subgrid physics models that converge and regulate at higher masses.
Bianca Azartash-Namin +8 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Stellar feedback-regulated black hole growth: driving factors from nuclear to halo scales [PDF]
, 2022 Lindsey Byrne +6 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Low- and High-velocity O vi in Milky Way-like Galaxies: The Role of Stellar Feedback
The Astrophysical JournalMilky Way-type galaxies are surrounded by a warm-hot gaseous halo containing a considerable amount of baryons and metals. The kinematics and spatial distribution of highly ionized ion species such as O vi can be significantly affected by supernova (SN ...
Zhijie Zhang +9 more
doaj +1 more source
A Parameter Space Exploration of High-resolution Numerically Evolved Early Type Galaxies Including AGN Feedback and Accurate Dynamical Treatment of Stellar Orbits [PDF]
, 2022 Luca Ciotti +6 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
KINEMATICS OF EXTREMELY METAL-POOR GALAXIES: EVIDENCE FOR STELLAR FEEDBACK [PDF]
The Astrophysical Journal, 2017 The extremely metal-poor (XMP) galaxies analyzed in a previous paper have large star-forming regions with a metallicity lower than the rest of the galaxy. Such a chemical inhomogeneity reveals the external origin of the metal-poor gas fueling star formation, possibly indicating accretion from the cosmic web.
A. Olmo-García +7 more
openaire +3 more sources
The Astrophysical JournalA fundamental question regarding the evolution of dwarf spheroidal galaxies is the identification of the key physical mechanisms responsible for gas depletion.
Roberto Hazenfratz +3 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source