Results 111 to 120 of about 22,322 (295)

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Quasi-Periodic Flares from Star-Accretion Disc Collisions

, 2009
We present simulated results of quasi-periodic flares generated by the inelastic collisions of a star bound to a super-massive black hole (SMBH) and its attendant accretion disc.
Alexander, Armitage, Baganoff, Bardeen, Blandford, Bower, Bromley, Carter, Ciufolini, Cunningham, Cunningham, Dabrowski, Damour, Damour, Damour, Damour, Eisenhauer, Evans, Fanton, Frank, Fuerst, Genzel, Genzel, Ghez, Ghez, Ghez, Ghez, Gierlinski, Gillessen, Karas, Karas, Kippenhahn, Kojima, Komossa, Komossa, Komossa, Laor, Lehto, Lindquist, Lixin (Jane) Dai, Miller, Misner, Nayakshin, Nilsson, Norman, Ostriker, Pariev, Perry, Peters, Piran, Rauch, Rauch, Rees, Rees, Reynolds, Roger Blandford, Schödel, Schödel, Semerák, Shen, Spruit, Steven V. Fuerst, Syer, Thorne, Wagoner, Wagoner, Zentsova, Zurek   +67 more
core   +1 more source

FLARE: A Framework for Stellar Flare Forecasting Using Stellar Physical Properties and Historical Records

Proceedings of the Thirty-Fourth International Joint Conference on Artificial Intelligence
Stellar flare events are critical observational samples for astronomical research; however, recorded flare events remain limited. Stellar flare forecasting can provide additional flare event samples to support research efforts. Despite this potential, no specialized models for stellar flare forecasting have been proposed to date.
Zhu, Bingke, Wang, Xiaoxiao, Jia, Minghui, Tao, Yihan, Kong, Xiao, Luo, Ali, Chen, Yingying, Tang, Ming, Wang, Jinqiao   +8 more
openaire   +2 more sources

Solar and Stellar Flares: Questions and Problems [PDF]

International Astronomical Union Colloquium, 1989
AbstractAlthough progress has been made in understanding certain aspects of the physics of solar and stellar flares, there are a number of topics which, in the author's opinion, still pose a problem. We summarize these topics here.
openaire   +1 more source

Defining Optimally Safe and Effective Blood Levels of Hydroxychloroquine in Lupus: An Important Step Toward Precision Drug Monitoring

Arthritis &Rheumatology, EarlyView.
Objective Using a hydroxychloroquine (HCQ) dose of 5 mg/kg/day in systemic lupus erythematosus (SLE) is associated with a higher risk of flares; HCQ blood level monitoring could be a better way to adjust the HCQ dose. We studied the upper threshold for a reference range of HCQ levels to inform routine monitoring.
Shivani Garg, Benoît Blanchet, Yann Nguyen, Fauzia Hollnagel, Ada Clarke, Michelle Petri, Murray B. Urowitz, John G. Hanly, Caroline Gordon, Sang‐Cheol Bae, Juanita Romero‐Diaz, Jorge Sanchez‐Guerrero, Ann E. Clarke, Sasha Bernatsky, Daniel J. Wallace, David A. Isenberg, Anisur Rahman, Joan T. Merrill, Paul R. Fortin, Dafna D. Gladman, Ian N. Bruce, Ellen M. Ginzler, Mary Anne Dooley, Rosalind Ramsey‐Goldman, Susan Manzi, Andreas Jönsen, Graciela S. Alarcón, Ronald F. Van Vollenhoven, Cynthia Aranow, Véronique Le Guern, Meggan Mackay, Guillermo Ruiz‐Irastorza, S. Sam Lim, Murat Inanc, Kenneth C. Kalunian, Søren Jacobsen, Christine A. Peschken, Diane L. Kamen, Anca Askanase, Jill Buyon, Julie Chezel, Alicja Puszkiel, Nathalie Costedoat‐Chalumeau   +42 more
wiley   +1 more source

EFTE-SOAR: Two Giant M Dwarf Flares with Rapid Spectroscopic Follow-up

The Astronomical Journal
We present time-series optical spectroscopy of two stellar flares with complex multi-peaked light curves: a $2.{1}_{-.3}^{+.4}\times 1{0}^{34}$ erg flare from an M8 ultra-cool dwarf, and a $1.{5}_{-.2}^{+.2}\times 1{0}^{35}$ erg superflare from an M4 ...
Hank Corbett, Nathan Galliher, Amy Glazier, Ramses Gonzalez Chavez, Nicholas M. Law, Ward S. Howard, Alan Vasquez Soto, Jeffrey K. Ratzloff, Robert Quimby   +8 more
doaj   +1 more source

Combined ultraviolet studies of astronomical sources [PDF]

Ultraviolet studies of astronomical sources are discussed. Some studies utilized IVE data. Non-radiative shock at the edge of the Cygnses Loop, stellar flares, local interestellar medium, hot galaxies, stellar mass ejection, contact binaries, double ...
Dupree, A. K., Giampapa, M. S., Hartmann, L. W., Huchra, J. P., Noyes, R. W., Raymond, J. C.   +5 more
core   +1 more source

Orbital parameters of supergiant fast X-ray transients

, 2010
Supergiant fast X-ray transient (SFXT) is a new class of the high mass X-ray binary that shows short X-ray flares. The physical mechanism of SFXT short flares is still open for discussion.
Augello, Bird, Bodaghee, Bozzo, Bozzo, Castor, Clark, Clark, Corbet, Corbet, Ducci, Hill, Howk, in ’t Zand, Jain, Kaper, Koh, Kreykenbohm, Kudritzki, La Parola, Leahy, Leyder, Nagase, Oskinova, Rahoui, Rampy, Romano, Romano, Romano, Romano, Romano, Romano, Runacres, S. Karino, Sguera, Sguera, Sidoli, Sidoli, Sidoli, Smith, Walter, Watson, White, Zurita Heras   +43 more
core   +1 more source

Hydrodynamic Models of Solar and Stellar Flares [PDF]

International Astronomical Union Colloquium, 1989
AbstractThis paper discusses the hydrodynamic modeling of flaring plasma confined in magnetic loops and its objectives within the broader scope of flare physics. In particular, the Palermo-Harvard model is discussed along with its applications to the detailed fitting of X-ray light curves of solar flares and to the simulation of high-resolution Caxix ...
openaire   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source