Results 31 to 40 of about 67,610 (340)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Searching for Low-mass Stars with Magnetically Induced Hyperinflated Radii

The Astrophysical Journal
Precise empirical estimates of stellar radii have revealed that the radii of certain low-mass stars are inflated relative to stellar structure predictions: the largest inflations occur in magnetically active stars.
D. J. Mullan, J. MacDonald
doaj   +1 more source

Stable magnetic fields in stellar interiors [PDF]

Astronomy & Astrophysics, 2006
19 pages, 24 figures, submitted to A& ...
Braitwaite, J., Nordlund, Å.
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Butterfly diagram of a Sun-like star observed using asteroseismology

, 2018
Stellar magnetic fields are poorly understood but are known to be important for stellar evolution and exoplanet habitability. They drive stellar activity, which is the main observational constraint on theoretical models for magnetic field generation and ...
Bazot, M., Benomar, O., Christensen-Dalsgaard, J., Gizon, L., Mary, D., Nielsen, M. B., Petit, P., Sreenivasan, K. R., White, T. R.   +8 more
core   +3 more sources

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Magnetic Fields in M-dwarf Members of the Pleiades Open Cluster Using APOGEE Spectra

The Astrophysical Journal
Average magnetic field measurements are presented for 62 M-dwarf members of the Pleiades open cluster, derived from Zeeman-enhanced Fe i lines in the H band.
Fábio Wanderley, Katia Cunha, Oleg Kochukhov, Verne V. Smith, Diogo Souto, Lyra Cao, Kevin Covey, Steven R. Majewski, Cintia Martinez, Philip S. Muirhead, Marc Pinsonneault, C. Allende Prieto, Keivan G. Stassun   +12 more
doaj   +1 more source

The Effects of Rotation, Metallicity, and Magnetic Field on the Islands of Failed Supernovae

The Astrophysical Journal, 2023
Failed supernovae (FSN) are a possible channel for the formation of heavy stellar-mass black holes ( M _BH > ∼30 M _⊙ ). However, the effects of metallicity, rotation, and magnetic field on the islands of explodabilty of massive stars are not clear. Here,
Lei Li, Chunhua Zhu, Sufen Guo, Helei Liu, Guoliang Lü   +4 more
doaj   +1 more source

Local Circumstellar Magnetic Fields Around Evolved Stars [PDF]

, 2002
I argue that the presence of magnetic fields around evolved stars, e.g., asymptotic giant branch stars, and in PNe, does not necessarily imply that the magnetic field plays a global dynamical role in shaping the circumstellar envelope.
Soker, Noam
core   +3 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source