Results 41 to 50 of about 5,710 (349)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Magnetic Fields in M-dwarf Members of the Pleiades Open Cluster Using APOGEE Spectra

The Astrophysical Journal
Average magnetic field measurements are presented for 62 M-dwarf members of the Pleiades open cluster, derived from Zeeman-enhanced Fe i lines in the H band.
Fábio Wanderley, Katia Cunha, Oleg Kochukhov, Verne V. Smith, Diogo Souto, Lyra Cao, Kevin Covey, Steven R. Majewski, Cintia Martinez, Philip S. Muirhead, Marc Pinsonneault, C. Allende Prieto, Keivan G. Stassun   +12 more
doaj   +1 more source

The Effects of Rotation, Metallicity, and Magnetic Field on the Islands of Failed Supernovae

The Astrophysical Journal, 2023
Failed supernovae (FSN) are a possible channel for the formation of heavy stellar-mass black holes ( M _BH > ∼30 M _⊙ ). However, the effects of metallicity, rotation, and magnetic field on the islands of explodabilty of massive stars are not clear. Here,
Lei Li, Chunhua Zhu, Sufen Guo, Helei Liu, Guoliang Lü   +4 more
doaj   +1 more source

The large-scale magnetic fields of planet-hosting solar-type stars [PDF]

, 2017
Stellar magnetic fields and their associated phenomena influence stellar behaviour and evolution, and potentially have significant impacts on any surrounding planetary system.
Mengel, Matthew W.
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Simplified Model of the Solar Magnetic Field

The Astrophysical Journal
This paper considers a structure consisting of two rings of magnetic dipoles symmetrical relative to the equatorial plane as a possible model for the source of the solar magnetic field.
Igor G. Kosakovskij
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Consequences of spontaneous reconnection at a two-dimensional non-force-free current layer

, 2012
Magnetic neutral points, where the magnitude of the magnetic field vanishes locally, are potential locations for energy conversion in the solar corona.
E. R. Priest, Hood, Alan William, Parnell, Clare Elizabeth, Priest, Eric Ronald, Longcope, Dana, J. Fuentes-Fernández, C. E. Parnell, A. W. Hood, Fuentes Fernandez, Jorge, D. W. Longcope   +9 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source