Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Constraints on the Faint End of the Galaxy Stellar Mass Function at z ≃ 4–8 from Deep JWST Data
We analyze a sample of 3300 galaxies between redshifts z ≃ 3.5 and z ≃ 8.5 selected from James Webb Space Telescope (JWST) images in the Hubble Ultra Deep Field and UKIDSS Ultra Deep Survey field, including objects with stellar masses as low as ≃10 ^8 M ...
Rafael Navarro-Carrera +5 more
doaj +1 more source
HIERARCHICAL GALAXY GROWTH AND SCATTER IN THE STELLAR MASS–HALO MASS RELATION [PDF]
The relation between galaxies and dark matter halos reflects the combined effects of many distinct physical processes. Observations indicate that the z = 0 stellar mass–halo mass (SMHM) relation has remarkably small scatter in stellar mass at fixed halo ...
Meng Gu (顾梦), C. Conroy, P. Behroozi
semanticscholar +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
The high mass end of the stellar mass function: dependence on stellar population models and agreement between fits to the light profile [PDF]
We quantify the systematic effects on the stellar mass function that arise from assumptions about the stellar population, as well as how one fits the light profiles of the most luminous galaxies at z∼0.1.
M. Bernardi +7 more
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
What does (not) drive the variation of the low-mass end of the stellar initial mass function of early-type galaxies [PDF]
Barbosa Ce +11 more
openalex +1 more source
TDCOSMO VIII: Cosmological distance measurements in light of the mass-sheet degeneracy -- forecasts from strong lensing and IFU stellar kinematics [PDF]
Akın Yıldırım +3 more
openalex +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
A stellar-mass black hole population in the globular cluster NGC 6101? [PDF]
Dalessandro et al. observed a similar distribution for blue straggler stars and main-sequence turn-off stars in the Galactic globular cluster NGC 6101, and interpreted this feature as an indication that this cluster is not mass-segregated. Using direct N-
Miklos Peuten +4 more
semanticscholar +1 more source

