Results 111 to 120 of about 284,450 (301)

Stellar mass functions of galaxies, disks and spheroids at z~0.1

open access: yes, 2016
We present the stellar mass functions (SMF) and mass densities of galaxies, and their spheroid and disk components in the local (z~0.1) universe over the range 8.9
Bluck, Asa F. L.   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Constraints on the Faint End of the Galaxy Stellar Mass Function at z ≃ 4–8 from Deep JWST Data

open access: yesThe Astrophysical Journal
We analyze a sample of 3300 galaxies between redshifts z ≃ 3.5 and z ≃ 8.5 selected from James Webb Space Telescope (JWST) images in the Hubble Ultra Deep Field and UKIDSS Ultra Deep Survey field, including objects with stellar masses as low as ≃10 ^8 M ...
Rafael Navarro-Carrera   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The SL2S Galaxy-scale Lens Sample. V. Dark Matter Halos and Stellar IMF of Massive Early-type Galaxies out to Redshift 0.8

open access: yes, 2014
We investigate the cosmic evolution of the internal structure of massive early-type galaxies over half of the age of the Universe. We perform a joint lensing and stellar dynamics analysis of a sample of 81 strong lenses from the SL2S and SLACS surveys ...
Auger, Matthew W.   +6 more
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Parametrizing the Stellar Haloes of Galaxies

open access: yes, 2014
We study the stellar haloes of galaxies out to 70-100 kpc as a function of stellar mass and galaxy type by stacking aligned $r$ and $g$ band images from a sample of 45508 galaxies from SDSS DR9 in the redshift range $0.06\,\le\,z\,\le\,0.1$ and in the ...
D'Souza, R.   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Galaxy And Mass Assembly: Stellar Mass Estimates

open access: yes, 2011
Accepted for publication in MNRAS. 35 pages; 21 figures including 6 in 2 appendices -- v2. corrected three extremely embarrassing typos in coauthors' names as they appeared in the arXiv metadata; manuscript text is ...
Taylor, E.   +34 more
openaire   +3 more sources

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