Results 91 to 100 of about 55,503 (265)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2009 It has been known for some time now that rapidly-rotating solar-like stars possess the stellar equivalent of solar prominences. These may be three orders of magnitude more massive than their solar counterparts, and their ejection from the star may form a
Gregory, Scott G.; id_orcid +3 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Independence of Stellar Mass-loss Rates on Stellar Activity Based on Solar Observations [PDF]
, 2013 Stellar mass-loss rates are an important input ingredient for stellar evolution models since they determine stellar evolution parameters such as stellar spin-down and increase in stellar luminosity through the lifetime of a star.
Cohen, Ofer (5268880), Cohen, Ofer
core +1 more source
The Astrophysical JournalThe formation and evolution of planetary systems are linked to their host stellar environment. In this study, we employ a pebble-accretion-based planet population synthesis model to explore the correlation between planetary properties and stellar mass ...
Mengrui Pan +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Continuous stellar mass-loss in
, 2001 We present an N-body computer code -aimed at studies of galactic dynamics - with a CPU-efficient algorithm for a continuous (i.e. time-dependent) stellar mass-loss. First, we summarize available data on stellar mass-loss and derive the long-term (20 Gyr)
F. Combes, B. Jungwiert, J. Palouš
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Astrophysical JournalWe investigate the stellar shape and size–mass relationship of X-ray-selected active galactic nucleus (AGN) host galaxies using the high angular resolution and deep sensitivity in the near-infrared of the COSMOS-Web JWST survey field. We present the rest-
Bovornpratch Vijarnwannaluk +21 more
doaj +1 more source