Results 191 to 200 of about 286,710 (351)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Testing galaxy formation models with galaxy stellar mass functions [PDF]

, 2016
Seunghwan Lim, H. J. Mo, T.-W. Lan, Brice Ménard   +3 more
openalex   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

B-177 Selective and sensitive quantitation of 18 steroids in human serum using Thermo Scientific™ Stellar™ mass spectrometer [PDF]

Jingshu Guo, Lauren Bishop, Courtney Patterson, Alan Atkins, Kathryn L. Hassell   +4 more
openalex   +1 more source

A Planetary Mass and Stellar Radius Relationship for Exoplanets Orbiting Red Giants [PDF]

, 2018
Jonathan H. Jiang, Sheldon Zhu
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

A machine learning approach to galaxy properties: joint redshift–stellar mass probability distributions with Random Forest [PDF]

, 2021
Sunil Mucesh, W G Hartley, A. Palmese, O. Lahav, L Whiteway, Asa F. L. Bluck, A. Alarcon, A. Amon, K Bechtol, G. M. Bernstein, A. Carnero Rosell, M. Carrasco Kind, A. Choi, K. Eckert, S. Everett, D. Gruen, R. A. Gruendl, I. Harrison, Erica Huff, N.P. Kuropatkin, I Sevilla-Noarbe, E Sheldon, B Yanny, M. Aguena, S Allam, D. Bacon, E. Bertin, S Bhargava, D Brooks, J. Carretero, F. J. Castander, C Conselice, M. Costanzi, M. Crocce, L. da Costa, M. E. S. Pereira, J. De Vicente, S. Desai, H. T. Diehl, A Drlica-Wagner, A. E. Evrard, I. Ferrero, B Flaugher, P. Fosalba, J Frieman, J. García-Bellido, E. Gaztañaga, D. W. Gerdes, J Gschwend, G. Gutiérrez, S. R. Hinton, D L Hollowood, K Honscheid, D J James, K. Kuehn, M Lima, Hai-Nan Lin, M. A. G. Maia, P. Melchior, F. Menanteau, R Miquel, R. Morgan, F Paz-Chinchón, A. A. Plazas, E. Sánchez, V Scarpine, M Schubnell, S. Serrano, M. Smith, E. Suchyta, G. Tarlé, D. Thomas, C. To, T N Varga, R. D. Wilkinson   +74 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A hybrid stellar mass black-hole optimization framework for finding significant biclusters using average Kendall rank correlation. [PDF]

Sci Rep
Balamurugan R.
europepmc   +1 more source

Impact of the Accretion Disk Thickness on the Polarization of the Thermal Emission from Stellar Mass Black Holes

, 2023
Andrew West, H. Krawczynski
openalex   +1 more source