Results 181 to 190 of about 111,751 (340)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The Stellar Initial Mass Function: Constraints from Young Clusters and Theoretical Perspectives [PDF]

, 1999
Michael R. Meyer, Fred C. Adams, Lynne A. Hillenbrand, John M. Carpenter, Richard B. Larson   +4 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The stellar mass function of Praesepe

The Astrophysical Journal, 1995
D. M. Williams, G. H. Rieke, J. R. Stauffer   +2 more
openaire   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Photometric Objects Around Cosmic Webs (PAC). VI. High Satellite Fraction of Quasars

The Astrophysical Journal
The Photometric objects Around Cosmic webs (PAC) approach developed in Xu et al. has the advantage of making full use of spectroscopic and deeper photometric surveys.
Shanquan Gui, Kun Xu, Y. P. Jing, Donghai Zhao, Hongyu Gao   +4 more
doaj   +1 more source

The Stellar Initial Mass Function in the Giant HII Region NGC 595

, 1996
E. M. Malumuth, William H. Waller, J. W. Parker   +2 more
openalex   +1 more source

The ATLAS3D project – XX. Mass–size and mass–σ distributions of early-type galaxies: bulge fraction drives kinematics, mass-to-light ratio, molecular gas fraction and stellar initial mass function [PDF]

, 2013
Michele Cappellari, Richard M. McDermid, Katherine Alatalo, Leo Blitz, Maxime Bois, F. Bournaud, Martin Bureau, Alison F. Crocker, Roger L. Davies, Timothy A. Davis, P. T. de Zeeuw, Pierre–Alain Duc, Éric Emsellem, Sadegh Khochfar, Davor Krajnović, H. Kuntschner, Raffaella Morganti, Thorsten Naab, Tom Oosterloo, M. Sarzi, Nicholas Scott, P. Serra, Anne-Marie Weijmans, Lisa M. Young   +23 more
openalex   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The bulge–halo conspiracy in massive elliptical galaxies: implications for the stellar initial mass function and halo response to baryonic processes [PDF]

, 2014
Aaron A. Dutton, Tommaso Treu
openalex   +1 more source