Results 131 to 140 of about 409,343 (365)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Testing the Rossby Paradigm: Weakened Magnetic Braking in Early K-type Stars

The Astrophysical Journal
There is an intricate relationship between the organization of large-scale magnetic fields by a stellar dynamo and the rate of angular momentum loss due to magnetized stellar winds. An essential ingredient for the operation of a large-scale dynamo is the
Travis S. Metcalfe, Pascal Petit, Jennifer L. van Saders, Thomas R. Ayres, Derek Buzasi, Oleg Kochukhov, Keivan G. Stassun, Marc H. Pinsonneault, Ilya V. Ilyin, Klaus G. Strassmeier, Adam J. Finley, Rafael A. García, Daniel Huber, Yuxi (Lucy) Lu, Victor See   +14 more
doaj   +1 more source

The Coronal Structure of AB Doradus

, 2010
We perform a numerical simulation of the corona of the young, rapidly rotating K0 dwarf AB Doradus using a global MHD model. The model is driven by a surface map of the radial magnetic field constructed using Zeeman-Doppler Imaging.
Barnes, Cohen, Cohen, Cohen, Donati, Donati, G. A. J. Hussain, García-Alvarez, Guirado, Hussain, Hussain, J. J. Drake, Krishnamurthi, Kuerster, Luhman, López-Santiago, Maggio, Matranga, Mestel, O. Cohen, Pakull, Schatzmann, Schmitt, T. I. Gombosi, V. L. Kashyap, Vilhu, Wood, Wood, Zuckerman   +28 more
core   +1 more source

First Asteroseismic Analysis of the Globular Cluster M80: Multiple Populations and Stellar Mass Loss [PDF]

, 2023
Madeline Howell, S. W. Campbell, Dennis Stello, Gayandhi M De Silva   +3 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

High-velocity Blue-shifted Fe xxv Heα Line during a Superflare of the RS Canum Venaticorum–type Star IM Peg

The Astrophysical Journal Letters
The Monitor of All-sky X-ray Image (MAXI) detected a superflare, releasing 5 × 10 ^37 erg in 2−10 keV, of the RS CVn-type star IM Peg at 10:41 UT on 2023 July 23 with its Gas Slit Camera (2−30 keV).
Shun Inoue, Wataru Buz Iwakiri, Teruaki Enoto, Hiroyuki Uchida, Miki Kurihara, Masahiro Tsujimoto, Yuta Notsu, Kenji Hamaguchi, Keith Gendreau, Zaven Arzoumanian, Takeshi Go Tsuru   +10 more
doaj   +1 more source

The Great Escape II: Exoplanet Ejection from Dying Multiple Star Systems

, 2012
Extrasolar planets and belts of debris orbiting post-main-sequence single stars may become unbound as the evolving star loses mass. In multiple star systems, the presence or co-evolution of the additional stars can significantly complicate the prospects ...
Tout, Christopher A., Veras, Dimitri
core   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Active Galactic Nucleus Star Dynamics Under the Influence of Outflow–Ambient Interactions

The Astrophysical Journal
Stars with outflows interacting with ambient gas experience accelerations arising from the gravitational feedback induced by the interaction structure.
Muxin Liu, Lile Wang, Peng Peng
doaj   +1 more source

On The Maximum Mass of Stellar Black Holes

, 2010
We present the spectrum of compact object masses: neutron stars and black holes that originate from single stars in different environments. In particular, we calculate the dependence of maximum black hole mass on metallicity and on some specific wind ...
Ashley Ruiter, Belczynski, Belczynski, Belczynski, Bulik, Casares, Cassisi, Chris L. Fryer, Francesca Valsecchi, Fryer, Fryer, Gies, Hamann, Heger, Heger, Herrero, Jarrod R. Hurley, Jorick S. Vink, King, Krzysztof Belczynski, Kudritzki, Kudritzki, Limongi, Madhusudhan, Massey, Miller, Miller, Nieuwenhuijzen, Nugis, Ohsuga, Orosz, Pakull, Podsiadlowski, Prestwich, Silverman, Smith, Tomasz Bulik, Tout, Vazquez, Zhang, Ziolkowski   +40 more
core   +2 more sources