Results 121 to 130 of about 5,593,868 (306)

Stellar Magnetic Storm Induced Magnetospheric Polarity Reversals: A Potential Diagnostic for Distinguishing Unmagnetized and Magnetized (Exo)planets

open access: yesThe Astrophysical Journal
(Exo)planetary environments are forced by stellar activity, which manifest through variable radiation, particle and magnetic fluxes, stellar winds, flares, and magnetic storms known as coronal mass ejections (CMEs). Recent studies have shown that planets
Sakshi Gupta, Souvik Roy, Dibyendu Nandy
doaj   +1 more source

Fictions, Conditionals, and Stellar Astrophysics [PDF]

open access: yes, 2013
This article argues in favour of an inferential role for fictions in scientific modelling. The argument proceeds by means of a detailed case study, namely models of the internal structure of stars in stellar astrophysics.
Suárez, Mauricio, Mauricio Suárez
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

High-velocity Blue-shifted Fe xxv Heα Line during a Superflare of the RS Canum Venaticorum–type Star IM Peg

open access: yesThe Astrophysical Journal Letters
The Monitor of All-sky X-ray Image (MAXI) detected a superflare, releasing 5 × 10 ^37 erg in 2−10 keV, of the RS CVn-type star IM Peg at 10:41 UT on 2023 July 23 with its Gas Slit Camera (2−30 keV).
Shun Inoue   +10 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Constraining the Stellar Mass Function in the Galactic Center via Mass Loss from Stellar Collisions [PDF]

open access: yes
The dense concentration of stars and high-velocity dispersions in the Galactic center imply that stellar collisions frequently occur. Stellar collisions could therefore result in significant mass loss rates.
Abraham Loeb, Douglas Rubin
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Active Galactic Nucleus Star Dynamics Under the Influence of Outflow–Ambient Interactions

open access: yesThe Astrophysical Journal
Stars with outflows interacting with ambient gas experience accelerations arising from the gravitational feedback induced by the interaction structure.
Muxin Liu, Lile Wang, Peng Peng
doaj   +1 more source

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