Results 111 to 120 of about 5,593,868 (306)
Explaining individual variation in patterns of mass loss in breeding birds [PDF]
, 2006 Background Studies of birds have a disproportionate representation in the literature on life-history evolution, because of the (apparent) ease with which the costs and benefits can be quantified and manipulated. During reproduction, birds frequently show
Alasdair I Houston +5 more
core +3 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Dance to Demise—How Massive Stars May Form Dense Circumstellar Shells before Explosion
The Astrophysical JournalWe investigate the evolution of red supergiant (RSG) progenitors of core-collapse supernovae (SNe) with initial masses between 12 and 20 M _⊙ , focusing on the effects of enhanced mass loss due to pulsation-driven instabilities in their envelopes and ...
Sutirtha Sengupta +2 more
doaj +1 more source
The Real-Time Evolution of V4334 Sgr
Galaxies, 2018 V4334 Sgr (Sakurai’s object) is an enigmatic evolved star that underwent a very late thermal pulse a few years before its discovery in 1996. It ejected a new hydrogen-deficient nebula in the process. The source has been observed continuously since,
Peter A. M. van Hoof +7 more
doaj +1 more source
Stellar and total mass in early-type lensing galaxies [PDF]
, 2005 For 18 well-observed gravitationally lensed QSOs, we compare new nonparametric mass profiles for the lensing galaxies with stellar population models derived from published Hubble Space Telescope photometry.
Ferreras, I. +5 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Searching for Stellar-feedback-driven Outflow Signatures: A Deep Dive into NGC 3741
The Astrophysical JournalStellar feedback drives winds and outflows critical to the baryon cycles of low-mass galaxies whose shallow gravitational potential wells make them particularly susceptible to mass and metal loss through outflows. However, spatially resolved observations
Lexi N. Gault +7 more
doaj +1 more source
The nature and origin of disky elliptical galaxies [PDF]
, 2002 The observational trend that disky elliptical galaxies exhibit younger luminosity- weighted ages than boxy ellipticals is investigated. The presence of a possible young stellar disk embedded in these galaxies is explored by comparing kinematics derived ...
McDermid, Richard Morgan
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source