Results 101 to 110 of about 46,211 (288)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Astrophysical JournalRecent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense ...
Ambreesh Khurana, Sourav Chatterjee
doaj +1 more source
Seeds to success: Growing heavy black holes in dense star clusters
Astronomy & AstrophysicsContext. The observational dearth of black holes (BHs) with masses between ∼100 and 100 000 M⊙ raises questions about the nature of intermediate-mass black holes (IMBHs).
Paiella Lavinia +3 more
doaj +1 more source
Modified evolution of stellar binaries from supermassive black hole binaries
, 2017 The evolution of main sequence binaries resided in the galactic centre is influenced a lot by the central super massive black hole (SMBH). Due to this perturbation, the stars in a dense environment are likely to experience mergers or collisions through ...
Liu, Bin, Wang, Yi-Han, Yuan, Ye-Fei
core +1 more source
Stellar mergers and common-envelope evolution
This is a pre-print of a chapter for the Encyclopedia of Astrophysics (edited by I. Mandel, section editor F.R.N.
Schneider, Fabian R. N. +2 more
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Maximum Mass Ratio of Hierarchical Binary Black Hole Mergers May Cause the q–χeff Correlation
The Astrophysical Journal LettersRegardless of their initial spins, the merger of two roughly equal mass black holes (BHs) produces a remnant BH of dimensionless spin 0.69. Such remnants can merge with other BHs in dense stellar environments and produce hierarchical mergers.
Aditya Vijaykumar +2 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Astrophysical JournalRecent studies show that the eccentricity distribution of wide binaries (semimajor axis ≳10 ^3 au) observed by Gaia tends to favor large eccentricities more strongly than the canonical thermal distribution ( P ( e ) ∝ e )—such distributions are termed ...
Yubo Su, Bin Liu, Siyao Xu
doaj +1 more source
Common-envelope evolution and stellar mergers
, 2016 We discuss the various phases encountered during common-envelope (CE) evolution, starting with the criterion for dynamical mass transfer and the onset of a common-envelope phase, the main spiralin phase and ending with the final merging of the binary components (in cases where the envelope is not ejected earlier).
openaire +2 more sources