Results 61 to 70 of about 197,228 (295)

Physics of Compact Advanced Stellarators [PDF]

open access: yes, 2001
Compact optimized stellarators offer novel solutions for confining high-beta plasmas and developing magnetic confinement fusion. The 3-D plasma shape can be designed to enhance the MHD stability without feedback or nearby conducting structures and provide drift-orbit confinement similar to tokamaks.
Zarnstorff, M. C.   +33 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Model for Eruptive Mass Loss in Massive Stars

open access: yesThe Astrophysical Journal
Eruptive mass loss in massive stars is known to occur, but the mechanism(s) are not yet well understood. One proposed physical explanation appeals to opacity-driven super-Eddington luminosities in stellar envelopes.
Shelley J. Cheng   +5 more
doaj   +1 more source

Massive stars: stellar models and stellar yields, impact on Galactic Archaeology

open access: yes, 2017
The physics of massive stars depends (at least) on convection, mass loss by stellar winds, rotation, magnetic fields and multiplicity. We briefly discuss the impact of the first three processes on the stellar yields trying to identify some guidelines for
Choplin, Arthur   +3 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Near-core Acoustic Glitches Are Not Oscillatory: Consequences for Asteroseismic Probes of Convective Boundary Mixing

open access: yesThe Astrophysical Journal, 2023
Asteroseismology has been used extensively in recent years to study the interior structure and physical processes of main-sequence stars. We consider prospects for using pressure modes (p-modes) near the frequency of maximum oscillation power to probe ...
Christopher J. Lindsay   +2 more
doaj   +1 more source

Astrophysical Rates for Explosive Nucleosynthesis: Stellar and Laboratory Rates for Exotic Nuclei [PDF]

open access: yes, 2009
A selected overview of stellar effects and reaction mechanisms with relevance to the prediction of astrophysical reaction rates far off stability is provided.Comment: 4 pages, 2 figures (contining 2 subfigures each); Proceedings of 10th Intl ...
Abbondanno   +24 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A Core-sensitive Mixed f/g-mode of the Sun Predicted by Wave Topology and Hydrodynamical Simulation

open access: yesThe Astrophysical Journal Letters
Helioseismology has revolutionized our understanding of the Sun by analyzing its global oscillation modes. However, the solar core remains elusive, limiting a full understanding of its evolution.
Arthur Le Saux   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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