Results 211 to 220 of about 108,892 (343)

The Progenitor Systems of Classical Novae in M31. [PDF]

Astrophys J
Abelson CS, Badenes C, Chomiuk L, Williams BF, Breivik K, Galbany L, Jiménez-Palau C.   +6 more
europepmc   +1 more source

Old-Aged Stellar Population Distance Indicators [PDF]

, 2018
Rachael L. Beaton, Giuseppe Bono, V. F. Braga, M. Dall’Ora, G. Fiorentino, In Sung Jang, C. E. Martínez-Vázquez, Noriyuki Matsunaga, M. Monelli, J. Neeley, M. Salaris   +10 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

The emergence of globular clusters and globular-cluster-like dwarfs. [PDF]

Nature
Taylor ED, Read JI, Orkney MDA, Kim SY, Pontzen A, Agertz O, Rey MP, Andersson EP, Collins MLM, Yates RM.   +9 more
europepmc   +1 more source

The elliptical galaxy NGC 5044: Stellar population and ionized gas [PDF]

, 2004
M. G. Rickes, M. G. Pastoriza, Ch. Bonato   +2 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Extreme properties of a compact and massive accreting black hole host in the first 500 Myr. [PDF]

Nat Commun
Tripodi R, Martis N, Markov V, Bradač M, Di Mascia F, Cammelli V, D'Eugenio F, Willott C, Curti M, Bhatt M, Gallerani S, Rihtaršič G, Singh J, Gaspar G, Harshan A, Judež J, Merida RM, Desprez G, Sawicki M, Goovaerts I, Muzzin A, Noirot G, Sarrouh GTE, Abraham R, Asada Y, Brammer G, Estrada-Carpenter V, Felicioni G, Fujimoto S, Iyer K, Mowla L, Strait V.   +31 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Evidence of star cluster migration and merger in dwarf galaxies. [PDF]

Nature
Poulain M, Smith R, Duc PA, Marleau FR, Habas R, Durrell PR, Fensch J, Lim S, Müller O, Paudel S, Sánchez-Janssen R.   +10 more
europepmc   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source