Results 81 to 90 of about 6,518 (266)

REQUIEM-2D Methodology: Spatially Resolved Stellar Populations of Massive Lensed Quiescent Galaxies from Hubble Space Telescope 2D Grism Spectroscopy [PDF]

, 2020
Mohammad Akhshik, Katherine E. Whitaker, Gabriel Brammer, Guillaume Mahler, Keren Sharon, Joel Leja, Matthew Bayliss, Rachel Bezanson, Michael D. Gladders, Allison W. S. Man, Erica J. Nelson, Jane R. Rigby, Francesca Rizzo, Sune Toft, Sarah Wellons, Christina C. Williams   +15 more
openalex   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Fluorine Abundances in Local Stellar Populations

The Astronomical Journal
We present the first fluorine measurements in 12 normal K giants belonging to the Galactic thin and thick disks using spectra obtained with the Phoenix infrared spectrometer on the 2.1 m telescope at Kitt Peak. Abundances are determined from the (1−0) R9
K. E. Brady, C. A. Pilachowski, V. Grisoni, Z. G. Maas, K. A. Nault   +4 more
doaj   +1 more source

Age determination of the nuclear stellar population of Active Galactic Nuclei using Locally Weighted Regression [PDF]

, 2003
Trilce Estrada-Piedra, J. P. Torres-Papaqui, R. Terlevich, Olac Fuentes, E. Terlevich   +4 more
openalex   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Azimuthal Misalignments in Stellar Warp Structure as Dynamical Tracers of Mergers in Milky Way–like Galaxies

The Astrophysical Journal Letters
We investigate the origin of warps in stellar disks using high-resolution Milky Way analogs from the IllustrisTNG50 simulation. Focusing on galaxies that experienced a major merger, we identify a characteristic azimuthal misalignment between the warp ...
Lekshmi Thulasidharan, Elena D’Onghia, Robert Benjamin   +2 more
doaj   +1 more source

Stellar Population Models and Individual Element Abundances. I. Sensitivity of Stellar Evolution Models [PDF]

, 2007
Aaron Dotter, Brian Chaboyer, Jason W. Ferguson, Hyun‐Chul Lee, Guy Worthey, Darko Jevremović, E. Baron   +6 more
openalex   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source