Results 101 to 110 of about 1,811,299 (294)

Semiresolved Stellar Populations as Distance Indicators

The Astrophysical Journal Letters
Galaxy distances are central to our understanding of the Universe. Despite the success of existing approaches, independent and complementary methods remain valuable for testing systematic effects and extending the applicability range of different ...
Ignacio Martín-Navarro, Patricia Iglesias Navarro, Francesco La Barbera, Alexandre Vazdekis, Michael A. Beasley, Marc Huertas-Company, ChangHoon Hahn, Luis Peralta de Arriba, Isaac Alonso Asensio, Eirini Angeloudi, Miguel Cerviño, Katja Fahrion, Tereza Jerabkova, Jesús Falcón-Barroso, Sebastián F. Sánchez, Prashin Jethwa   +15 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Fluorine Abundances in Local Stellar Populations

The Astronomical Journal
We present the first fluorine measurements in 12 normal K giants belonging to the Galactic thin and thick disks using spectra obtained with the Phoenix infrared spectrometer on the 2.1 m telescope at Kitt Peak. Abundances are determined from the (1−0) R9
K. E. Brady, C. A. Pilachowski, V. Grisoni, Z. G. Maas, K. A. Nault   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Stellar Population of R136 [PDF]

Symposium - International Astronomical Union, 1999
The luminous, compact star cluster R136 in the Large Magellanic Cloud is 300 times more spatially concentrated than a typical OB association and contains at least 39 O3 stars, the most massive of which is ~150 M⊙. Yet, the stellar IMF for 2.8–120 M⊙ is normal. The massive stars are 1–2 Myrs old, and Wolf-Rayet stars are not evolved.
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Stellar Populations in the Central Parsecs of Galactic Bulges Central Stellar Populations

, 2004
We present Hubble Space Telescope blue spectra at intermediate spectral resolution for the nuclei of 23 nearby disk galaxies. These objects were selected to have nebular emission in their nuclei, and span a range of emission-line classifications as well as Hubble types.
Sarzi, Marc, Rix, Hans-Walter, Shields, Joseph C., Ho, Luis C., Barth, Aaron J., Rudnick, Gregory, Filippenko, Alexei V., Sargent, Wallace L. W.   +7 more
openaire   +2 more sources