Results 91 to 100 of about 104,545 (289)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Characterizing stellar populations in spiral disks

open access: yes, 2006
It is now possible to measure detailed spectral indices for stellar populations in spiral disks. We propose to interpret these data using evolutionary synthesis models computed from the Star Formation Histories obtained from chemical evolutionary models.
D. Beauchamp   +8 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Multiple Stellar Populations in Globular Clusters

open access: yes, 2017
Globular Clusters (GCs) exhibit star-to-star variations in specific elements (e.g., He, C, N, O, Na, Al) that bare the hallmark of high temperature H burning. These abundance variations can be observed spectroscopically and also photometrically, with the
Bastian, Nate, Lardo, Carmela
core   +1 more source

The Stellar Population of M17

open access: yesThe Astrophysical Journal, 2008
The stellar content of M17 has been investigated by multicolor photometry and spectroscopy. Various independent estimates yield a distance of 2.1 ± 0.2 kpc. The ratio of total-to-selective extinction is R = 3.9. Within a projected area of 3.6 × 3.7 pc, there are several thousand stars.
Hoffmeister, V. H.   +6 more
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Testing the Breakdown of the Asteroseismic Scaling Relations in Luminous Red Giants

open access: yesThe Astrophysical Journal
Nearly all cool, evolved stars are solar-like oscillators, and fundamental stellar properties can be inferred from these oscillations with asteroseismology.
Amanda L. Ash   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Impulsive Mixing of Stellar Populations in Dwarf Spheroidal Galaxies

open access: yesThe Astrophysical Journal
We study the response of mono-energetic stellar populations with initially isotropic kinematics to impulsive and adiabatic changes to an underlying dark matter potential.
Raphaël Errani   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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