Results 91 to 100 of about 1,883,435 (259)
The Oldest Stellar Populations and the Age of the Universe
, 2002 The study of the oldest stellar populations in the Galaxy provides important cosmological information (e.g. a lower limit to the age of the Universe) and helps constraining models of galaxy formation.
C. Cacciari
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Fluorine Abundances in Local Stellar Populations
The Astronomical JournalWe present the first fluorine measurements in 12 normal K giants belonging to the Galactic thin and thick disks using spectra obtained with the Phoenix infrared spectrometer on the 2.1 m telescope at Kitt Peak. Abundances are determined from the (1−0) R9
K. E. Brady +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Studying Stellar Systems with Classical Pulsators [PDF]
, 2018 Classical Cepheids and RR Lyrae are very important primary distance indicators and stellar population tracers, thanks to the relations between pulsation properties and intrinsic stellar parameters. Through the theoretical prediction of these relations as
MARCONI, Marcella +4 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Dissecting stellar populations with manifold learning
Context. Different stellar populations may be identified through differences in chemical, kinematic, and chronological properties, suggesting the interplay of various physical mechanisms that led to their origin and subsequent evolution.
A. Miglio +3 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Astrophysical JournalWe present FrankenBlast , a customized and improved version of the Blast web application. FrankenBlast associates transients to their host galaxies, performs host photometry, and runs a innovative spectral energy distribution fitting code to constrain ...
Anya E. Nugent +7 more
doaj +1 more source