Results 191 to 200 of about 220,237 (344)

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Origins and lifetimes of secular and tidal bars in simulated disc galaxies. [PDF]

Mon Not R Astron Soc
Frosst M, Obreschkow D, Ludlow A, Fraser-McKelvie A.   +3 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Isotropic fluid structures and role of non-metricity on their dynamics governed by an electric charge: A theoretical study. [PDF]

PLoS One
Naseer T, Sharif M, Waqas M, Andrade J, Emara A.   +4 more
europepmc   +1 more source

FitteR for Accretion ProPErties of T Tauri stars (FRAPPE): A new approach to use Class III spectra to derive stellar and accretion properties [PDF]

R. A. B. Claes, J. Campbell-White, C. F. Manara, A. Frasca, A. Natta, J. M. Alcalá, A. Armeni, M. Fang, Joshua B. Lovell, B. Stelzer, L. Venuti, M. C. Wyatt, A. Queitsch   +12 more
openalex   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The fragmentation properties of massive star-forming regions in 30Dor-10 at 2000 au resolution. [PDF]

Nat Commun
Traficante A, Jiménez-Donaire MJ, Indebetouw R, Wong T, Nucara A, Klessen RS, Hennebelle P, Lebreuilly U, Mininni C, Molinari S, Sabbi E, Soler JD.   +11 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Formation time-scales for stellar bars in diverse galactic discs. [PDF]

Mon Not R Astron Soc
Frosst M, Obreschkow D, Ludlow A.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source