Results 211 to 220 of about 220,237 (344)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Flare-driven habitability: Expanding life's potential around low-mass stars. [PDF]

Innovation (Camb)
Gao DY, Liu HG, Yang M, Zhou JL.
europepmc   +1 more source

Looking into the faintEst WIth MUSE (LEWIS): on the nature of ultra-diffuse galaxies in the Hydra I cluster. V. Integrated stellar population properties

Doll, Goran, Buttitta, Chiara, Iodice, Enrichetta, Ferré-Mateu, Anna, Falcòn-Barroso, Jesus, Martìn-Navarro, Ignacio, Paolillo, Maurizio, Rossi, Luca, Forbes, Duncan A., Spiniello, Chiara, Hartke, Johanna, Gullieuszik, Marco, Arnaboldi, Magda, Cantiello, Michele, Corsini, Enrico Maria, D'Ago, Giuseppe, Hilker, Michael, La Marca, Antonio, Mieske, Steffen, Mirabile, Marco, Rejkuba, Marina, Spavone, Marilena   +21 more
openalex   +1 more source

Understanding stellar properties through conceptual modelling

In this workshop we present three lesson activities to teach core (astro)physics concepts at pre-university level which students find difficult to grasp with traditional interventions: star properties, star states and the fusion-gravity balance. In each activity, students construct and simulate a conceptual cause-effect model.
Kragten, Marco, Holt, Joanna, Bredeweg, Bert   +2 more
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Structural Prior-Guided Weighted Low-Rank Denoising for Short-Wave Infrared Star Images. [PDF]

Sensors (Basel)
Wu C, Wang K, Wang T, Du G, Li X, Chen F.   +5 more
europepmc   +1 more source

Using spectroscopic data to disentangle stellar population properties [PDF]

, 2003
N. Cardiel, J. Gorgas, P. Sánchez-Blázquez, A. J. Cenarro, S. Pedraz, G. Bruzual, J. Klement   +6 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A universal brown dwarf desert formed between planets and stars. [PDF]

Proc Natl Acad Sci U S A
Cui K, Xiao GY, Feng F, Liu B, Nayakshin S, Hall C, Guo K, Lai D, Ogihara M, Rui Y, Boss AP, Butler RP, Xuan Y.   +12 more
europepmc   +1 more source

Stellar and Gas Properties of High HiMass-to-Light Ratio Galaxies in the Local Universe [PDF]

, 2006
B. E. Warren, Helmut Jerjen, B. Koribalski   +2 more
openalex   +1 more source