Results 51 to 60 of about 6,039,312 (259)

Stellar magnetism : empirical trends with age and rotation [PDF]

open access: yes, 2014
AAV acknowledges support from a Royal Astronomical Society Fellowship and from the Swiss National Science Foundation via an Ambizione Fellowship. SGG acknowledges support from the Science and Technology Facilities Council (STFC) via an Ernest Rutherford ...
G. Hussain   +47 more
core   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Stellar Cruise Control: Weakened Magnetic Braking Leads to Sustained Rapid Rotation of Old Stars

open access: yesThe Astrophysical Journal
Despite a growing sample of precisely measured stellar rotation periods and ages, the strength of magnetic braking and the degree of departure from standard (Skumanich-like) spin-down have remained persistent questions, particularly for stars more ...
Nicholas Saunders   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Variation of Circumstellar Parameters through Early Stellar Evolution

open access: yesThe Astrophysical Journal
We report on the evolution of extinction, mass accretion rate, and spectral index from analysis of SpeX observations and AllWISE spectral energy distributions, compared to stellar parameters (mass, age, and veiling) derived from analysis of previously ...
Michael Connelley   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Using Gravity as an Age Indicator for Young Stars

open access: yesThe Astrophysical Journal Letters
The age of a young star is difficult to measure and yet is a fundamental property that is essential for understanding stellar evolution. Accurate age indicators across the early phases of low-mass stars are scarce and often rely on properties of the ...
Michael Connelley   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Solar and stellar rotation [PDF]

open access: yes, 2007
Workshop on Solar and Stellar Physics through Eclipses -- MAR 27-29, 2006 -- Ankara Univ, ORSEM Campus, Side, Antalya, TURKEYThe secular evolution of the stellar rotation through angular momentum loss, driven by the stellar wind, and the consequences of ...
Demircan, O., Filiz-Ak, N., Eker, Z.
core   +1 more source

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