Results 111 to 120 of about 3,384 (302)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Stellar motions along I = 60 - 240 and I = 150-330 inhomogeneous frequency distribution of spectral types

open access: yesAnuário do Instituto de Geociências, 1990
Applications of the x² test to the frequency distribution of spectral types show a slight predominance of A, F and G stars running approximately along I = 60 - 240 ; along the orthogonal direction, there seems to occur a preponderance of K and M stars.
openaire   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

On the late spectral types of cataclysmic variable secondaries

open access: yes, 2000
9 pages, Latex file, uses mn.styInternational audienceWe investigate why the spectral type of most cataclysmic variable (CV) secondaries is significantly later than that of a ZAMS star with the same mean density.
Baraffe, Isabelle, Kolb, U.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Near Infrared Spectral Classification of Young Stellar Objects in Nearby Star Forming Region

open access: yes, 2016
We present spectral classification of young stellar objects (YSOs), in near infrared (NIR) low resolution spectroscopy. These sources have been previously examined for the presence of spectral features, which have conformed them as YSO candidates.
Soto, Edith
core  

The effect of the environment on the evolution of galaxy colours [PDF]

open access: yes, 2006
In chapter 1 of this thesis, I give a brief overview of the birth of modern cosmology and the growth of the current paradigm. I then go on to describe the different types of galaxies, the star formation rates within them and give some notes about galaxy ...
Davies, Gregory Tudor
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Stellar parameters of young brown dwarfs

open access: yes, 2011
We present X-shooter observations of two brown dwarf candidates. We focus on the determination of stellar parameters and their errors. The targets, an accreting class II and a non-accreting class III objects, are members of the σ Orionis star-forming ...
Rigliaco E   +6 more
core   +1 more source

Observations of Extremely Metal-poor O Stars: Weak Winds and Constraints for Evolution Models

open access: yesThe Astrophysical Journal
Metal-poor massive stars drive the evolution of low-mass galaxies, both locally and at high redshift. However, quantifying the feedback they impart to their local surroundings remains uncertain because models of stellar evolution, mass loss, and ionizing
O. Grace Telford   +5 more
doaj   +1 more source

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