Results 91 to 100 of about 5,043,235 (296)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

M-dwarf stellar winds : the effects of realistic magnetic geometry on rotational evolution and planets [PDF]

open access: yes, 2014
AAV acknowledges support from a Royal Astronomical Society Fellowship. JM acknowledges support from a fellowship of the Alexander von Humboldt foundation.We perform three-dimensional numerical simulations of stellar winds of early-M-dwarf stars.
Morin, J.   +11 more
core   +1 more source

First JWST/NIRSpec Spectroscopy of O Stars in the Small Magellanic Cloud

open access: yesThe Astrophysical Journal Letters
Determining how much mass is removed by stellar winds is crucial to understanding massive star evolution and feedback. However, traditional spectroscopic diagnostics in the UV and optical are not sensitive enough to characterize weak stellar winds of OB ...
Armin Mang Román   +12 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Hydrogen Atom Collision Processes in Cool Stellar Atmospheres : Effects on Spectral Line Strengths and Measured Chemical Abundances in Old Stars

open access: yes, 2012
The precise measurement of the chemical composition of stars is a fundamental problem relevant to many areas of astrophysics. State-of-the-art approaches attempt to unite accurate descriptions of microphysics, non-local thermodynamic equilibrium (non-LTE)
Barklem, Paul S.,
core   +1 more source

Morphological Feature Distances among the Spectral Types of SDSS Galaxies

open access: yesThe Astrophysical Journal
This study investigates the morphological feature distances among various spectral types of galaxies from the Sloan Digital Sky Survey, including strong and weak active galactic nuclei (AGN), quasi-stellar objects (QSOs), quiescent, and star-forming ...
Duho Kim, Garreth Martin
doaj   +1 more source

VARIABLE STARS IN ARCHIVAL SCHMIDT CAMERA OBSERVATIONS: CROSS-MATCHING AND ML CLASSIFICATION

open access: yesEurasian Physical Technical Journal
Digitized archival astronomical observations provide a valuable basis for the study of variable stars and their long-term behavior. This work presents an analysis of variable stars based on archival photometric data obtained with a Schmidt camera at the
I. Izmailova   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Identification of New Be Stars from LAMOST Data Release 11 Based on Deep Learning

open access: yesThe Astrophysical Journal Supplement Series
Be stars are rapidly rotating B-type stars that exhibit Balmer emission lines in their optical spectra, which makes them crucial for studying stellar evolution and circumstellar disk structures.
Lei Tan   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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