Results 11 to 20 of about 1,317,911 (218)
Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment [PDF]
Stem Cells International, 2017 Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated cells, and to interact with its environment to maintain a balance between quiescence, proliferation, and regeneration. While adult Stem Cells display these properties when participating in tissue homeostasis, Cancer Stem Cells (CSCs) behave as their ...
Pedro M. Aponte, Andrés Caicedo
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Stemming vision loss with stem cells [PDF]
Journal of Clinical Investigation, 2010 Dramatic advances in the field of stem cell research have raised the possibility of using these cells to treat a variety of diseases. The eye is an excellent target organ for such cell-based therapeutics due to its ready accessibility, the prevalence of vasculo- and neurodegenerative diseases affecting vision, and the availability of animal models to ...
Valentina, Marchetti +3 more
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Stemness, cancer, and cancer stem cells [PDF]
Cell Cycle, 2008 The ability of cancers to grow indefinitely has fueled the idea that cancer and stem cells may have common underlying mechanisms. Detailed gene expression maps have now shown the diversity and distinctiveness in gene expression programs associated with stemness in embryonic and adult stem cells. These maps have further revealed a shared transcriptional
David J, Wong +2 more
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Science, 2007 Two converging events took place on 9 August that ought to have the scientific community scratching its collective head. One of these is an anniversary: On that date in 2001, President George W. Bush signed an Executive Order banning any use of federal funds to support research on stem cells (save, of course, for those 78 preexisting cell lines, only ...
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To STEM or not to STEM? That is not the question
Cypriot Journal of Educational Sciences, 2018 The aim of this study is to identify the faults in Science, Technology, Engineering and Mathematics (STEM) education and to provide an approach to how these deficiencies can be eliminated. The STEM approach can provide students with an interdisciplinary point of view to gain creativity, critical thinking, high-level skills of thinking and problem ...
Kubat, U., Guray, E.
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Hematopoietic stem cell metabolism and stemness
Blood Science, 2019 AbstractHematopoietic stem cells (HSCs) are considered to originate from the aorta-gonad-mesonephros, migrate into fetal liver for a rapid expansion, and eventually reside into a unique hypoxic bone marrow niche, where they maintain their homeostasis throughout their life span.
Dan Huang +4 more
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The EMBO Journal, 2005 Stem cells are unique in their capacity to self-renew and generate differentiated progeny to maintain tissues throughout life. A common molecular program for stem cells has remained elusive. We discuss what the molecular logic of stemness may be. We suggest that it may not be coupled to distinct cellular properties such as self-renewal or multipotency,
Harald, Mikkers, Jonas, Frisén
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Stemming on STEM: A STEM Education Framework for Students with Disabilities
Journal of Science Education for Students with Disabilities, 2016 There has been increased attention paid to science, technology, engineering, and mathematics also known as STEM. The focus on STEM has been both educational and occupational. Unfortunately, students with disabilities perform below their peers without disabilities in math and science.
Hwang, Jiwon, Taylor, Jonte C
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The role of microRNAs in stemness of cancer stem cells
Oncology Reviews, 2013 Cancer is one of the most important diseases of humans, for which no cure has been found so far. Understanding the causes of cancer can pave the way for its treatment. Alteration in genetic elements such as oncogenes and tumor suppressor genes results in cancer.
Seyed Mohammad Ali Hosseini Rad +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
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